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Articles Published Processes
4/9/2021 5:27:04 AM | Browse: 487 | Download: 900
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Received |
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2021-01-09 09:07 |
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Peer-Review Started |
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2021-01-09 09:08 |
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To Make the First Decision |
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Return for Revision |
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2021-01-24 23:45 |
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Revised |
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2021-01-30 06:24 |
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Second Decision |
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2021-03-03 03:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-11 02:58 |
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Articles in Press |
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2021-03-11 02:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-18 01:30 |
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Publish the Manuscript Online |
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2021-04-09 05:27 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Laboratory Technology |
| Manuscript Type |
Therapeutic and Diagnostic Guidelines |
| Article Title |
Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Masaki Nagaya, Koki Hasegawa, Ayuko Uchikura, Kazuaki Nakano, Masahito Watanabe, Kazuhiro Umeyama, Hitomi Matsunari, Kenji Osafune, Eiji Kobayashi, Hiromitsu Nakauchi and Hiroshi Nagashima |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Masaki Nagaya, MD, PhD, Professor, Meiji University International Institute for Bio-Resource Research, Meiji University, 1-1-1 Higashimita, Tama-ku, Kawasaki 214-8571, Kanagawa, Japan. m2nagaya@gmail.com |
| Key Words |
Pancreatic islet; Diabetes mellitus; Pig; Transgenic; Genetically engineering; Transplantation; Xenotransplantation |
| Core Tip |
Safer and more effective therapeutics are urgently required for managing the diabetes epidemic. Mice have been used predominantly as preclinical models for basic research on diabetes, although murine models are not ideally suited for translating basic knowledge into clinical applications. This article discusses features that attest to the attractiveness of genetically modified porcine models of diabetes for testing novel treatment strategies using recent technical advances. |
| Publish Date |
2021-04-09 05:27 |
| Citation |
Nagaya M, Hasegawa K, Uchikura A, Nakano K, Watanabe M, Umeyama K, Matsunari H, Osafune K, Kobayashi E, Nakauchi H, Nagashima H. Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes. World J Diabetes 2021; 12(4): 306-330 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i4/306.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i4.306 |
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