Publication Name	World Journal of Clinical Cases
Manuscript ID	62446
Country	Iran

Received	2021-01-08 18:24
Peer-Review Started	2021-01-08 18:26
To Make the First Decision
Return for Revision	2021-03-27 05:46
Revised	2021-04-07 10:02
Second Decision	2021-04-23 09:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-04-23 12:04
Articles in Press	2021-04-23 12:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-04-27 22:13
Typeset the Manuscript	2021-05-31 11:00
Publish the Manuscript Online	2021-06-11 09:22

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Infectious Diseases
Manuscript Type	Minireviews
Article Title	Dynamics of host immune responses to SARS-CoV-2
Manuscript Source	Invited Manuscript
All Author List	Reza Taherkhani, Sakineh Taherkhani and Fatemeh Farshadpour
ORCID	Author(s) ORCID Number Reza Taherkhani http://orcid.org/0000-0001-6499-0531 Sakineh Taherkhani http://orcid.org/0000-0003-3161-0963 Fatemeh Farshadpour http://orcid.org/0000-0002-8317-9573
Funding Agency and Grant Number
Corresponding Author	Fatemeh Farshadpour, PhD, Associate Professor, Department of Virology, Bushehr University of Medical Sciences, Moallem Street, Bushehr 7514633341, Iran. f.farshadpour@bpums.ac.ir
Key Words	SARS-CoV-2; COVID-19; Immune response; Antibody-dependent enhancement; Cytokine storm; Original antigenic sin
Core Tip	This study provides an overview on the possible role of immunopathologic phenomena, including antibody-dependent enhancement, cytokine storm, and original antigenic sin in severity and mortality of coronavirus disease-2019 (COVID-19). With the emergence of new challenges in the context of immunity to COVID-19, it is pivotal to characterize the dynamics of host immune responses to COVID-19, to develop efficient prophylactic and therapeutic tools. This begs the question of whether the effector mechanisms of the immune system are indeed potent or a possible contributing factor to developing more severe forms of COVID-19.
Publish Date	2021-06-11 09:22
Citation	Taherkhani R, Taherkhani S, Farshadpour F. Dynamics of host immune responses to SARS-CoV-2. World J Clin Cases 2021; 9(18): 4480-4490
URL	https://www.wjgnet.com/2307-8960/full/v9/i18/4480.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i18.4480

Full Article (PDF)	WJCC-9-4480.pdf
Full Article (Word)	WJCC-9-4480.docx
Manuscript File	62446-Review-Filipodia-CL2.docx
Answering Reviewers	62446-Answering reviewers.pdf
Audio Core Tip	62446-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	62446-Conflict-of-interest statement.pdf
Copyright License Agreement	62446-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	62446-Language certificate.pdf
Peer-review Report	62446-Peer-review(s).pdf
Scientific Misconduct Check	62446-Scientific misconduct check.pdf
Scientific Editor Work List	62446-Scientific editor work list.pdf
CrossCheck Report	62446-CrossCheck report.pdf