ISSN |
1948-9366 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Could neoadjuvant chemotherapy increase postoperative complication risk on laparoscopic total gastrectomy? A mono-institutional propensity score-matched study in China
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hao Cui, Jian-Xin Cui, Yu-Ning Wang, Bo Cao, Huan Deng, Ke-Cheng Zhang, Tian-Yu Xie, Wen-Quan Liang, Yi Liu, Lin Chen and Bo Wei |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Basic Research Program of China (973 Program) |
2019YFB1311505 |
National Natural Science Foundation of China |
81773135 |
National Natural Science Foundation of China |
82073192 |
Health Cultivating Foundation for Capital Citizens |
Z171100000417023 |
|
Corresponding Author |
Bo Wei, MD, PhD, Chief Doctor, Professor, Staff Physician, Department of General Surgery, Institute of General Surgery, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China. 18431143691@163.com |
Key Words |
Neoadjuvant chemotherapy; Gastric cancer; Laparoscope; Total gastrectomy; Morbidity |
Core Tip |
Neoadjuvant chemotherapy (NC) and laparoscopic gastrectomy are crucial parts of integrated perioperative treatment for gastric cancer. However, whether NC significantly affects surgical safety or postoperative complications of laparoscopic gastrectomy, especially laparoscopic total gastrectomy (LTG), remains unclear. In our study, we used the propensity-score matching method to compare short-term outcomes between LTG after NC (NC-LTG) and LTG alone. We found that despite a longer operation time and more blood loss in NC-LTG, indicating surgical difficulty, NC-LTG showed acceptable short-term outcomes compared to LTG, illustrating its safety and feasibility. |
Publish Date |
2021-05-21 01:58 |
Citation |
Cui H, Cui JX, Wang YN, Cao B, Deng H, Zhang KC, Xie TY, Liang WQ, Liu Y, Chen L, Wei B. Could neoadjuvant chemotherapy increase postoperative complication risk on laparoscopic total gastrectomy? A mono-institutional propensity score-matched study in China. World J Gastrointest Surg 2021; 13(5): 429-442 |
URL |
https://www.wjgnet.com/1948-9366/full/v13/i5/429.htm |
DOI |
https://dx.doi.org/10.4240/wjgs.v13.i5.429 |