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Articles Published Processes
5/6/2021 11:18:51 AM | Browse: 595 | Download: 1286
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Received |
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2021-01-26 17:51 |
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Peer-Review Started |
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2021-01-26 18:02 |
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To Make the First Decision |
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Return for Revision |
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2021-03-01 01:13 |
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Revised |
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2021-03-13 21:17 |
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Second Decision |
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2021-04-26 09:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-26 11:36 |
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Articles in Press |
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2021-04-26 11:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-04-29 14:49 |
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Publish the Manuscript Online |
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2021-05-06 11:18 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Role of insulin and insulin resistance in androgen excess disorders
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kursad Unluhizarci, Zuleyha Karaca and Fahrettin Kelestimur |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kursad Unluhizarci, MD, Professor, Department of Endocrinology, Erciyes University Medical School, Talas, Kayseri 38039, Türkiye. kursad@erciyes.edu.tr |
| Key Words |
Insulin; Insulin resistance; Hyperinsulinemia; Hyperandrogenism; Androgen excess |
| Core Tip |
In patients with insulin resistance not all the signaling pathways and the insulin responsive tissues are equally affected and some effects other than metabolic actions of insulin are overexpressed. Ovaries and the adrenal glands are two examples of tissues remaining sensitive to insulin actions where insulin may contribute to increased androgen secretion leading to androgen excess disorders. Therefore, the role and the contribution of hyperinsulinemia triggered by (selective) insulin resistance has paramount importance for elucidating the pathogenesis of these disorders and also to establish the right patient for insulin sensitizer therapy. |
| Publish Date |
2021-05-06 11:18 |
| Citation |
Unluhizarci K, Karaca Z, Kelestimur F. Role of insulin and insulin resistance in androgen excess disorders. World J Diabetes 2021; 12(5): 616-629 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i5/616.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i5.616 |
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