| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Helicobacter pylori infection and other bacteria in pancreatic cancer and autoimmune pancreatitis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Lumir Kunovsky, Petr Dite, Petr Jabandziev, Jiri Dolina, Jitka Vaculova, Martin Blaho, Martina Bojkova, Jana Dvorackova, Magdalena Uvirova, Zdenek Kala and Jan Trna |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Health of the Czech Republic |
NU20-03-00126 |
| Ministry of Health of the Czech Republic–conceptual development of research organization |
FNBr, 65269705, SUp 3/21 |
|
| Corresponding Author |
Jan Trna, MD, PhD, Associate Professor, Department of Gastroenterology and Digestive Endoscopy, Masaryk Memorial Cancer Institute, Žlutý kopec 7, Brno 65653, Czech Republic. jan.trna@mou.cz |
| Key Words |
Helicobacter pylori; Pancreatic cancer; Autoimmune pancreatitis; Carcinogenesis; Microbiome; Molecular mimicry |
| Core Tip |
Helicobacter pylori (H. pylori) is the causative agent for several diseases, most especially gastric and duodenal peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma of the stomach and also a number of extragastric manifestations. The role of H. pylori in the inflammation characteristic of autoimmune pancreatitis seems to be explained by a mechanism of molecular mimicry between several proteins (mostly enzymes) of H. pylori and pancreatic tissue. The topic is itself sufficiently significant to draw the interest of clinicians and inspire further systematic research. Next-generation sequencing could play an important role in investigating the microbiome as a potential diagnostic and prognostic biomarker for pancreatic cancer. |
| Publish Date |
2021-08-14 11:08 |
| Citation |
Kunovsky L, Dite P, Jabandziev P, Dolina J, Vaculova J, Blaho M, Bojkova M, Dvorackova J, Uvirova M, Kala Z, Trna J. Helicobacter pylori infection and other bacteria in pancreatic cancer and autoimmune pancreatitis. World J Gastrointest Oncol 2021; 13(8): 835-844 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i8/835.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i8.835 |
