Publication Name	World Journal of Clinical Cases
Manuscript ID	62646
Country	China

Received	2021-01-14 07:26
Peer-Review Started	2021-01-14 07:29
To Make the First Decision
Return for Revision	2021-02-11 06:12
Revised	2021-03-07 23:28
Second Decision	2021-03-26 06:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-03-29 20:35
Articles in Press	2021-03-29 20:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-04-05 00:45
Typeset the Manuscript	2021-04-29 03:21
Publish the Manuscript Online	2021-05-11 11:07

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Integrative & Complementary Medicine
Manuscript Type	Opinion Review
Article Title	COVID-19 combined with liver injury: Current challenges and management
Manuscript Source	Invited Manuscript
All Author List	Man-Ling Deng, Yong-Jun Chen, Mei-Ling Yang, Yi-Wen Liu, Hui Chen, Xiao-Qing Tang and Xue-Feng Yang
ORCID	Author(s) ORCID Number Man-Ling Deng http://orcid.org/0000-0001-7499-0826 Yong-Jun Chen http://orcid.org/0000-0002-2076-6295 Mei-Ling Yang http://orcid.org/0000-0001-8782-8959 Yi-Wen Liu http://orcid.org/0000-0001-9427-1482 Hui Chen http://orcid.org/0000-0001-8122-2438 Xiao-Qing Tang http://orcid.org/0000-0001-9151-3730 Xue-Feng Yang http://orcid.org/0000-0002-3470-0350
Funding Agency and Grant Number	Funding Agency Grant Number Novel Coronavirus Pneumonia Emergency Project of University of South China 2020-15 Novel Coronavirus Pneumonia Emergency Project of University of South China 2020-25 Fund Project of Hengyang City for Prevention and Control of COVID-19 202010031577 Key Research and Development Program of Hunan Province 2020SK3039 Key Research and Development Program of Hunan Province 2020SK3040
Corresponding Author	Xue-Feng Yang, MD, Full Professor, Department of Gastroenterology, The Affiliated Nanhua Hospital, Hengyang Medical College, University of South China, No. 336 Dongfeng Road, Zhuhui District, Hengyang 421002, Hunan Province, China. yxf9988@126.com
Key Words	SARS-CoV-2; COVID-19; Liver function; Liver injury; Pathogenesis; Treatment
Core Tip	The prevention and treatment of coronavirus disease 2019 (COVID-19) combined with liver injury faces many challenges: First, the definition of COVID-19 combined with liver injury is not clear, the selected parameters and the time of statistics are inconsistent, and finally the conclusions about the incidence rate are consistent; secondly, the etiology and mechanism of COVID- 19 combined liver injury are not clear and need to be studied in depth; third, there is a lack of effective treatment methods. This article aims at providing additional view at the incidence of COVID-19 associated liver injury and to explore the contemporary management modalities.
Publish Date	2021-05-11 11:07
Citation	Deng ML, Chen YJ, Yang ML, Liu YW, Chen H, Tang XQ, Yang XF. COVID-19 combined with liver injury: Current challenges and management. World J Clin Cases 2021; 9(15): 3487-3497
URL	https://www.wjgnet.com/2307-8960/full/v9/i15/3487.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i15.3487

Full Article (PDF)	WJCC-9-3487.pdf
Full Article (Word)	WJCC-9-3487.docx
Manuscript File	62646-Review-FilipodiaCL.docx
Answering Reviewers	62646-Answering reviewers.pdf
Audio Core Tip	62646-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	62646-Conflict-of-interest statement.pdf
Copyright License Agreement	62646-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	62646-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	62646-Language certificate.pdf
Peer-review Report	62646-Peer-review(s).pdf
Scientific Misconduct Check	62646-Bing-Wang JL-1.jpg
Scientific Misconduct Check	62646-Scientific misconduct check.pdf
Scientific Editor Work List	62646-Scientific editor work list.pdf
CrossCheck Report	62646-CrossCheck report.pdf