Publication Name	World Journal of Gastroenterology
Manuscript ID	6274
Country	Brazil

Received	2013-10-11 17:17
Peer-Review Started	2013-10-12 16:34
To Make the First Decision	2013-11-21 20:53
Return for Revision	2013-11-22 16:33
Revised
Second Decision	2014-01-05 14:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-05 15:19
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-27 15:29
Publish the Manuscript Online	2014-02-17 14:01

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs
Manuscript Source	Invited Manuscript
All Author List	Aline Cristina Targa Cadamuro, Ana Flávia Teixeira Rossi, Nathália Maciel Maniezzo and Ana Elizabete Silva
Funding Agency and Grant Number
Corresponding Author	Ana Elizabete Silva, PhD, Department of Biology, UNESP-São Paulo State University, Campus São José do Rio Preto, Rua Cristóvão Colombo, 2265, 15054-000 São José do Rio Preto, SP, Brazil. anabete@ibilce.unesp.br
Key Words	Helicobacter pylori; Inflammation; Virulence factors; Immune response; Gastric lesions; Gastric cancer; Gene expression; MicroRNAs
Core Tip	In this review, we focused some aspects of Helicobacter pylori (H. pylori) infection as bacterial virulence factor and mainly on modulation of host immune response and changes in the pattern of gene expression in H. pylori-infected gastric mucosa, with activation of gene transcription involved in inflammatory and immunological response, cell proliferation and apoptosis. We also highlighted the role of bacteria eradication for the normalization of gene expression levels. In addition, we addressed the recent involvement of different microRNAs in normal gastric mucosa, precancerous lesions, gastric cancer, and inflammatory processes induced by bacteria, showing deregulated expression.
Publish Date	2014-02-17 14:01
Citation	Cadamuro ACT, Rossi AFT, Maniezzo NM, Silva AE. Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs. World J Gastroenterol 2014; 20(6): 1424-1437
URL	http://www.wjgnet.com/1007-9327/full/v20/i6/1424.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i6.1424

Full Article (PDF)	WJG-20-1424.pdf
Full Article (Word)	WJG-20-1424.doc
Manuscript File	6274-Review.doc
Answering Reviewers	6274-Answering reviewers.pdf
Copyright License Agreement	6274-Copyright assigment.pdf
Peer-review Report	6274-Peer review(s).pdf
Scientific Editor Work List	6274-Scientific editor work list.doc