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9/3/2014 10:14:00 AM | Browse: 632 | Download: 332
Publication Name World Journal of Gastroenterology
Manuscript ID 6274
Country/Territory Brazil
Received
2013-10-11 17:17
Peer-Review Started
2013-10-12 16:34
To Make the First Decision
2013-11-21 20:53
Return for Revision
2013-11-22 16:33
Revised
Second Decision
2014-01-05 14:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-05 15:19
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-27 15:29
Publish the Manuscript Online
2014-02-17 14:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Topic Highlights
Article Title Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs
Manuscript Source Invited Manuscript
All Author List Aline Cristina Targa Cadamuro, Ana Flávia Teixeira Rossi, Nathália Maciel Maniezzo and Ana Elizabete Silva
Funding Agency and Grant Number
Corresponding author Ana Elizabete Silva, PhD, Department of Biology, UNESP-São Paulo State University, Campus São José do Rio Preto, Rua Cristóvão Colombo, 2265, 15054-000 São José do Rio Preto, SP, Brazil. anabete@ibilce.unesp.br
Keywords Helicobacter pylori; Inflammation; Virulence factors; Immune response; Gastric lesions; Gastric cancer; Gene expression; MicroRNAs
Core Tip In this review, we focused some aspects of Helicobacter pylori (H. pylori) infection as bacterial virulence factor and mainly on modulation of host immune response and changes in the pattern of gene expression in H. pylori-infected gastric mucosa, with activation of gene transcription involved in inflammatory and immunological response, cell proliferation and apoptosis. We also highlighted the role of bacteria eradication for the normalization of gene expression levels. In addition, we addressed the recent involvement of different microRNAs in normal gastric mucosa, precancerous lesions, gastric cancer, and inflammatory processes induced by bacteria, showing deregulated expression.
Publish Date 2014-02-17 14:01
Citation Cadamuro ACT, Rossi AFT, Maniezzo NM, Silva AE. Helicobacter pylori infection: Host immune response, implications on gene expression and microRNAs. World J Gastroenterol 2014; 20(6): 1424-1437
Url http://www.wjgnet.com/1007-9327/full/v20/i6/1424.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i6.1424
Full Article (PDF) WJG-20-1424.pdf
Full Article (Word) WJG-20-1424.doc
Manuscript File 6274-Review.doc
Answering Reviewers 6274-Answering reviewers.pdf
Copyright License Agreement 6274-Copyright assigment.pdf
Peer-review Report 6274-Peer review(s).pdf
Scientific Editor Work List 6274-Scientific editor work list.doc