| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Molecular alterations in pancreatic tumors
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Michela Visani, Giorgia Acquaviva, Antonio De Leo, Viviana Sanza, Lidia Merlo, Thais Maloberti, Alba A Brandes, Enrico Franceschi, Monica Di Battista, Michele Masetti, Elio Jovine, Sirio Fiorino, Annalisa Pession, Giovanni Tallini and Dario de Biase |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Dario de Biase, MSc, PhD, Assistant Professor, Department of Pharmacy and Biotechnology, University of Bologna, viale Ercolani 4/2, Bologna 40138, Italy. dario.debiase@unibo.it |
| Key Words |
Pancreatic tumors; Molecular alterations; Pancreatic ductal adenocarcinomas; Intraductal papillary mucinous neoplasm; Mutations; Molecular markers |
| Core Tip |
To date, in patients with pancreatic cancer there are not targetable molecules for personalized treatment in clinical practice. The introduction of multi-gene analysis approaches, as massive parallel sequencing, has provided a lot of useful information about the molecular characterization of pancreatic tumors. However, a huge amount of data needs to be properly managed to determine the information that is useful and correct. A deeper knowledge of the molecular alterations characterizing pancreatic neoplasms may lead to new potential therapeutic targets for these tumors. |
| Publish Date |
2021-05-27 09:41 |
| Citation |
Visani M, Acquaviva G, De Leo A, Sanza V, Merlo L, Maloberti T, Brandes AA, Franceschi E, Di Battista M, Masetti M, Jovine E, Fiorino S, Pession A, Tallini G, de Biase D. Molecular alterations in pancreatic tumors. World J Gastroenterol 2021; 27(21): 2710-2726 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i21/2710.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i21.2710 |
