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Articles Published Processes
6/8/2022 2:31:10 AM | Browse: 684 | Download: 1507
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Received |
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2022-01-27 20:53 |
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Peer-Review Started |
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2022-01-27 20:54 |
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First Decision by Editorial Office Director |
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2022-04-18 00:23 |
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Return for Revision |
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2022-04-18 00:23 |
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Revised |
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2022-04-24 11:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-05-23 03:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-05-28 07:03 |
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Articles in Press |
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2022-05-28 07:03 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-05-31 07:36 |
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Publish the Manuscript Online |
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2022-06-08 02:31 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Basic Study |
| Article Title |
Investigating the specificity of endothelin-traps as a potential therapeutic tool for endothelin-1 related disorders
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Arjun Jain, Kristof Bozovicar, Vidhi Mehrotra, Tomaz Bratkovic, Martin H Johnson and Ira Jha |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arjun Jain, MPhil, PhD, Research Scientist, . jain_arjun@yahoo.com |
| Key Words |
Endothelin-1; Endothelin-traps; Diabetes; Heart failure; Chronic kidney disease; Novel therapeutic |
| Core Tip |
This study verified the specificity of endothelin (ET)-traps, which are an Fc-based fusion protein that acts as a potential therapeutic for various cET-1 related disorders, including diabetes and chronic kidney disease. ET-traps, unlike ET receptor antagonists, do not completely block the ET system and hence have minimal side effects. ET-traps would help save millions of lives around the world. |
| Publish Date |
2022-06-08 02:31 |
| Citation |
Jain A, Bozovicar K, Mehrotra V, Bratkovic T, Johnson MH, Jha I. Investigating the specificity of endothelin-traps as a potential therapeutic tool for endothelin-1 related disorders. World J Diabetes 2022; 13(6): 434-441 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i6/434.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i6.434 |
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