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Articles Published Processes
6/11/2021 9:22:17 AM | Browse: 455 | Download: 665
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Received |
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2021-01-22 10:44 |
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Peer-Review Started |
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2021-01-22 10:47 |
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To Make the First Decision |
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Return for Revision |
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2021-03-02 00:45 |
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Revised |
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2021-03-15 13:41 |
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Second Decision |
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2021-05-06 14:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-05-06 14:26 |
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Articles in Press |
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2021-05-06 14:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-05-09 11:11 |
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Typeset the Manuscript |
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2021-06-07 07:07 |
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Publish the Manuscript Online |
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2021-06-11 09:22 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Role of exosomes in the diagnosis and treatment of colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yvette Umwali, Cong-Bo Yue, Abakundana Nsenga Ariston Gabriel, Yi Zhang and Xin Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81972005 |
| Natural Science Foundation of Shandong Province |
ZR2020MH238 |
| Shandong Medical and Health Technology Development Project |
2018WSB20002 |
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| Corresponding Author |
Xin Zhang, FRS, MD, PhD, Academic Fellow, Associate Professor, Department of Clinical Laboratory Diagnostic, Qilu Hospital, Cheeloo College of Medicine, Shandong University, No. 107 Wenhua West Road, Jinan 250012, Shandong Province, China. xinzhang@sdu.edu.cn |
| Key Words |
Colorectal cancer; Exosomes; Biomarker; Extracellular vesicle; Diagnosis |
| Core Tip |
Exosomes are extracellular vesicles that mediate intercellular communication. They contain molecules such as RNAs, DNA, lipids, and proteins whose role is essential in the pathogenesis of colorectal cancer (CRC). Exosomes derived from CRC are implicated in tumorigenesis, chemotherapy resistance, and metastasis. Besides, they can enhance CRC progression by increasing tumor cell proliferation, reducing apoptosis mechanistically through upregulation or downregulation of particular essential regulatory genes, or controlling several signaling pathways. Therefore, exosomes derived from CRCs are essential biomarkers and can be used in the diagnosis. |
| Publish Date |
2021-06-11 09:22 |
| Citation |
Umwali Y, Yue CB, Gabriel ANA, Zhang Y, Zhang X. Role of exosomes in the diagnosis and treatment of colorectal cancer. World J Clin Cases 2021; 9(18): 4467-4479 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i18/4467.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i18.4467 |
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