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Articles Published Processes
5/14/2021 9:21:55 AM | Browse: 308 | Download: 653
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Received |
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2021-01-22 08:22 |
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Peer-Review Started |
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2021-01-22 08:27 |
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To Make the First Decision |
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Return for Revision |
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2021-02-28 04:52 |
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Revised |
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2021-03-10 16:37 |
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Second Decision |
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2021-03-22 13:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-03-23 03:09 |
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Articles in Press |
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2021-03-23 03:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-04-04 10:41 |
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Typeset the Manuscript |
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2021-05-11 13:39 |
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Publish the Manuscript Online |
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2021-05-14 09:21 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Observational Study |
| Article Title |
Differential analysis revealing APOC1 to be a diagnostic and prognostic marker for liver metastases of colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Yu Shen, Fang-Ze Wei and Qian Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development (R&D) Program Project |
2019YFC1315705 |
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| Corresponding Author |
Qian Liu, MD, Chief Doctor, Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com |
| Key Words |
APOC1; Liver metastases; Colorectal cancer; Differentially expressed genes; Marker |
| Core Tip |
It is important to identify the diagnostic or prognostic markers for liver metastasis (LM) of colorectal cancer (CRC). Three datasets from NCBI Gene Expression Omnibus (GEO) were used to identify highly differentially expressed genes (HDEGs) between LM and tumor and LM and normal samples. Then, HDEGs of the three GEO database took the intersection. The prognostic value of these genes was screened through online tool, which finally showed that APOC1 was associated with prognosis of CRC. Analysis of the relationship with immune infiltration, tumor microenvironment and GSEA of APOC1 were strongly associated with CRC development. In conclusion, APOC1 is the biomarker both associated with diagnosis and prognosis of LM of CRC. |
| Publish Date |
2021-05-14 09:21 |
| Citation |
Shen HY, Wei FZ, Liu Q. Differential Analysis Revealing APOC1 to be a Diagnostic and Prognostic Marker for Liver Metastases of Colorectal Cancer. World J Clin Cases 2021; 9(16): 3880-3894 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i16/3880.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i16.3880 |
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