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Articles Published Processes
5/13/2021 10:05:39 AM | Browse: 1105 | Download: 3196
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Received |
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2021-01-23 02:55 |
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Peer-Review Started |
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2021-01-23 03:00 |
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First Decision by Editorial Office Director |
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2021-02-10 06:51 |
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Return for Revision |
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2021-02-10 06:51 |
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Revised |
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2021-02-17 10:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2021-04-12 07:08 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-04-14 17:09 |
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Articles in Press |
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2021-04-14 17:09 |
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Edit the Manuscript by Language Editor |
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2021-04-17 14:12 |
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Typeset the Manuscript |
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2021-05-11 01:18 |
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Publish the Manuscript Online |
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2021-05-13 10:05 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Observational Study |
| Article Title |
Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xia Liu, Yi-Wen Cheng, Li Shao, Shu-Hong Sun, Jian Wu, Qing-Hai Song, Hong-Sheng Zou and Zong-Xin Ling |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31700800 |
| National Natural Science Foundation of China |
81771724 |
| National S&T Major Project of China |
2018YFC2000500 |
| National Natural Science Foundation of China |
81790631 |
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| Corresponding Author |
Zong-Xin Ling, PhD, Professor, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang Univeristy, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. lingzongxin_lzx@163.com |
| Key Words |
Dysbiosis; Fasting blood glucose; Sequencing; Metabolism; Type 1 diabetes mellitus |
| Core Tip |
Alterations in the gut microbiota play vital roles in the development of autoimmune diseases such as type 1 diabetes mellitus (T1DM). Our present study explores the overall structure and composition of the fecal microbiota in Chinese children with T1DM and on its association with fasting blood glucose (FBG). We found that the bacterial diversity increased significantly in children with T1DM and that several key functional taxa were correlated with FBG. These key functional bacteria could be used as noninvasive diagnostic biomarkers to discriminate T1DM patients from healthy controls. This comprehensive investigation of the T1DM-associated fecal microbiota provides novel insights into the pathogenesis of T1DM. |
| Publish Date |
2021-05-13 10:05 |
| Citation |
Liu X, Cheng YW, Shao L, Sun SH, Wu J, Song QH, Zou HS, Ling ZX. Gut microbiota dysbiosis in Chinese children with type 1 diabetes mellitus: An observational study. World J Gastroenterol 2021; 27(19): 2394-2414
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| URL |
https://www.wjgnet.com/1007-9327/full/v27/i19/2394.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i19.2394 |
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