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Articles Published Processes
5/27/2021 9:41:33 AM | Browse: 633 | Download: 1365
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Received |
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2021-01-22 10:45 |
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Peer-Review Started |
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2021-01-25 05:30 |
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To Make the First Decision |
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Return for Revision |
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2021-02-28 02:51 |
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Revised |
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2021-03-26 12:49 |
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Second Decision |
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2021-04-28 07:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-28 08:07 |
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Articles in Press |
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2021-04-28 08:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-05-03 21:05 |
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Typeset the Manuscript |
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2021-05-24 11:14 |
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Publish the Manuscript Online |
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2021-05-27 09:41 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Direct antiviral agents in hepatitis C virus related liver disease: Don’t count the chickens before they’re hatched
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Manuscript Source |
Invited Manuscript |
All Author List |
Stella Compagnoni, Erica Maria Bruno, Giorgio Madonia, Marco Cannizzaro and Salvatore Madonia |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Salvatore Madonia, MD, Doctor, Doctor, Department of Internal Medicine, V. Cervello Hospital, Via Trabucco n 180, Palermo 90146, Italy. salvomadonia.sm@gmail.com |
Key Words |
Hepatitis C virus; Direct antiviral activity; Advanced cirrhosis; Liver cancer; Diabetes mellitus; Hepatitis C virus / Hepatitis B virus coinfection. |
Core Tip |
The landscape of treatment of hepatitis C virus (HCV) infection has completely changed since direct antiviral activities (DAAs) became available. Due to their efficacy in advanced fibrosis and their high tolerability, DAA use has been extended to patients with advanced cirrhosis and patients with severe comorbidities. Consequently, this review addresses the following questions: What benefits can be expected from eradicating HCV in patients who already have advanced liver disease? Are DAAs associated with an appreciable benefit in liver cancer? Can HCV treatment have favorable effects on the major concomitant disorders such as diabetes or cardiovascular disease? Is there any cause for concern when using DAAs in HCV patients with a concomitant HBV infection? |
Publish Date |
2021-05-27 09:41 |
Citation |
Compagnoni S, Bruno EM, Madonia G, Cannizzaro M, Madonia S. Direct antiviral agents in hepatitis C virus related liver disease: Don’t count the chickens before they’re hatched. World J Gastroenterol 2021; 27(21): 2771-2783 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i21/2771.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i21.2771 |
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