BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/29/2021 2:12:02 AM | Browse: 395 | Download: 830
 |
Received |
|
2021-01-22 14:36 |
 |
Peer-Review Started |
|
2021-01-22 14:40 |
 |
To Make the First Decision |
|
|
 |
Return for Revision |
|
2021-02-28 02:44 |
 |
Revised |
|
2021-03-13 13:43 |
 |
Second Decision |
|
2021-04-07 12:57 |
 |
Accepted by Journal Editor-in-Chief |
|
|
 |
Accepted by Executive Editor-in-Chief |
|
2021-04-07 20:42 |
 |
Articles in Press |
|
2021-04-07 20:42 |
 |
Publication Fee Transferred |
|
|
 |
Edit the Manuscript by Language Editor |
|
|
 |
Typeset the Manuscript |
|
2021-04-15 00:47 |
 |
Publish the Manuscript Online |
|
2021-04-29 02:12 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Repurposing metformin for the treatment of gastrointestinal cancer
|
Manuscript Source |
Invited Manuscript |
All Author List |
Ademar Dantas Cunha Júnior, Arinilda Campos Bragagnoli, Felipe Osório Costa and José Barreto Campello Carvalheira |
ORCID |
|
Funding Agency and Grant Number |
|
Corresponding Author |
José Barreto Campello Carvalheira, MD, PhD, Associate Professor, Department of Internal Medicine, Division of Oncology, University of Campinas (UNICAMP), Tessália Vieira Camargo, S/N, Campinas 13083-970, São Paulo, Brazil. jbcc@unicamp.br |
Key Words |
Antidiabetic treatments; Gastrointestinal tumors; Therapeutic target |
Core Tip |
Modulation of cell function into the neoplastic and around the microenvironment tissue are possible cancer targets utilized by metformin to raise chemotherapy's anti-tumor outcomes. Herein we review the studies that have demonstrated the likelihood of metformin as chemo and radiosensitizer, in addition to its chemopreventive and direct therapeutic activity in gastrointestinal tumors. |
Publish Date |
2021-04-29 02:12 |
Citation |
Cunha Júnior AD, Bragagnoli AC, Costa FO, Carvalheira JBC. Repurposing metformin for the treatment of gastrointestinal cancer. World J Gastroenterol 2021; 27(17): 1883-1904 |
URL |
https://www.wjgnet.com/1007-9327/full/v27/i17/1883.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v27.i17.1883 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345