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Articles Published Processes
5/20/2021 8:38:05 AM | Browse: 509 | Download: 1298
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Received |
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2021-01-27 09:07 |
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Peer-Review Started |
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2021-01-23 04:58 |
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To Make the First Decision |
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Return for Revision |
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2021-02-25 06:26 |
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Revised |
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2021-03-10 16:26 |
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Second Decision |
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2021-04-12 12:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-12 18:58 |
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Articles in Press |
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2021-04-12 18:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-04-20 09:13 |
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Typeset the Manuscript |
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2021-05-19 00:58 |
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Publish the Manuscript Online |
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2021-05-20 08:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Open reading frame 3 protein of hepatitis E virus: Multi-function protein with endless potential
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yong-Lin Yang and Yu-Chen Nan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31672534 |
| Key Project supported by Medical Science and technology development Foundation of Nanjing Department of Health |
ZKX19026 |
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| Corresponding Author |
Yu-Chen Nan, PhD, Associate Professor, Department of Preventive Veterinary Medicine, Northwest A&F University, No. 3 Taicheng Road, Yangling Demonstration Zone, Yangling 712100, Shaanxi Province, China. nanyuchen2015@nwsuaf.edu.cn |
| Key Words |
Hepatitis E virus; Zoonosis; Quasi-enveloped virion; Hepatitis E virus-open reading frame 3; Innate immunity |
| Core Tip |
Hepatitis E virus (HEV)-open reading frame (ORF) 3 was originally though as an accessory protein with limited function which is not essential for HEV replication. This view has been challenged by recent discoveries, such as HEV-ORF3-associated “Quasi-Enveloped” HEV particles, regulation of the host innate immune response and interference with host signaling pathways. More novel function of HEV-ORF3 will be revealed. |
| Publish Date |
2021-05-20 08:38 |
| Citation |
Yang YL, Nan YC. Open reading frame 3 protein of hepatitis E virus: Multi-function protein with endless potential. World J Gastroenterol 2021; 27(20): 2458-2473 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i20/2458.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i20.2458 |
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