Publication Name	World Journal of Hepatology
Manuscript ID	63116
Country	Spain

Received	2021-01-24 20:06
Peer-Review Started	2021-01-24 20:10
To Make the First Decision
Return for Revision	2021-03-08 06:33
Revised	2021-03-21 13:22
Second Decision	2021-05-08 09:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-05-08 09:57
Articles in Press	2021-05-08 09:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-07 04:55
Typeset the Manuscript	2021-06-19 09:38
Publish the Manuscript Online	2021-06-23 01:49

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Wilson's disease: Revisiting an old friend
Manuscript Source	Invited Manuscript
All Author List	Ana Lucena-Valera, Domingo Perez-Palacios, Rocio Muñoz-Hernandez, Manuel Romero-Gómez and Javier Ampuero
ORCID	Author(s) ORCID Number Ana Lucena-Valera http://orcid.org/0000-0003-1460-545X Domingo Perez-Palacios http://orcid.org/0000-0003-1460-544X Rocio Muñoz-Hernandez http://orcid.org/0000-0003-3765-6276 Manuel Romero-Gómez http://orcid.org/0000-0001-8494-8947 Javier Ampuero http://orcid.org/0000-0002-8332-2122
Funding Agency and Grant Number	Funding Agency Grant Number Consejería de Salud. Junta de Andalucía PI_0039_2017 Junta de andalucia 201799903406796
Corresponding Author	Javier Ampuero, MD, PhD, Doctor, Research Scientist, Department of Unit of Digestive Diseases, Hospital Universitario Virgen del Rocio, Avda. Manuel Siurot s/n, Sevilla 41014, Spain. jampuero-ibis@us.es
Key Words	Wilson´s disease; Copper; ATP7B; Ceruloplasmin; Chelator; Liver disease
Core Tip	Wilson’s disease (WD) is a rare metabolic disorder caused by the deposition of copper in the organism, particularly in the liver and the brain. Due to the symptoms and clinical presentation can be highly variable, WD is not always suspected. A detailed but practical review is presented to assist clinicians in diagnosing and managing WD.
Publish Date	2021-06-23 01:49
Citation	Lucena-Valera A, Perez-Palacios D, Muñoz-Hernandez R, Romero-Gómez M, Ampuero J. Wilson's disease: Revisiting an old friend. World J Hepatol 2021; 13(6): 634-649
URL	https://www.wjgnet.com/1948-5182/full/v13/i6/634.htm
DOI	https://dx.doi.org/10.4254/wjh.v13.i6.634

Full Article (PDF)	WJH-13-634.pdf
Full Article (Word)	WJH-13-634.docx
Manuscript File	63116_Auto_Edited-ZMG-Webster J[22911]-Clear.docx
Answering Reviewers	63116-Answering reviewers.pdf
Audio Core Tip	63116-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	63116-Conflict-of-interest statement.pdf
Copyright License Agreement	63116-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	63116-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	63116-Language certificate.pdf
Peer-review Report	63116-Peer-review(s).pdf
Scientific Misconduct Check	63116-Bing-Liu M-1.png
Scientific Misconduct Check	63116-Bing-Fan JR-2.png
Scientific Misconduct Check	63116-Scientific misconduct check.pdf
Scientific Editor Work List	63116-Scientific editor work list.pdf