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Articles Published Processes
8/26/2014 3:51:00 PM | Browse: 1045 | Download: 1251
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Received |
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2013-10-13 22:57 |
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Peer-Review Started |
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2013-10-15 13:57 |
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To Make the First Decision |
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2013-12-04 09:04 |
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Return for Revision |
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2013-12-04 21:23 |
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Revised |
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2013-12-29 14:16 |
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Second Decision |
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2014-03-05 14:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-05 15:19 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-18 14:02 |
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Typeset the Manuscript |
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2014-05-07 15:17 |
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Publish the Manuscript Online |
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2014-06-16 16:19 |
Category |
Oncology |
Manuscript Type |
Topic Highlights |
Article Title |
Prognostic and predictive significance of MSI in stages Ⅱ/Ⅲ colon cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Zacharenia Saridaki, John Souglakos and Vassilis Georgoulias |
Funding Agency and Grant Number |
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Corresponding Author |
John Souglakos, MD, PhD, Department of Medical Oncology, University General Hospital of Heraklion, Voutes, PO BOX 1352, 71110 Heraklion, Crete, Greece. georgsec@med.uoc.gr |
Key Words |
Microsatellite instability; Stage Ⅱ; Stage Ⅲ; Colon cancer; Predictive; Prognostic |
Core Tip |
Adjuvant chemotherapy in patients with stage Ⅱ colon cancer is still a subject of controversy. Stage Ⅱ tumors are highly heterogeneous, with five-year relative overall survival rates ranging from 58.4% to 87.5%. Recently reported European Society for Medical Oncology guidelines suggest that microsatellite instability (MSI) should be evaluated in stage Ⅱ colorectal cancer patients in order to contribute in treatment decision-making regarding chemotherapy administration. The current report critically evaluates the prognostic and predictive impact of MSI status in patients with stage Ⅱ and stage Ⅲ colon cancer. |
Publish Date |
2014-06-16 16:19 |
Citation |
Saridaki Z, Souglakos J, Georgoulias V. Prognostic and predictive significance of MSI in stages Ⅱ/Ⅲ colon cancer. World J Gastroenterol 2014; 20(22): 6809-6814 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i22/6809.htm |
DOI |
10.3748/wjg.v20.i22.6809 |
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