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7/12/2021 12:42:13 AM | Browse: 471 | Download: 826
Publication Name World Journal of Gastroenterology
Manuscript ID 63224
Country/Territory Australia
Received
2021-01-26 11:03
Peer-Review Started
2021-01-26 11:15
To Make the First Decision
Return for Revision
2021-02-27 17:42
Revised
2021-03-24 10:43
Second Decision
2021-06-15 12:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-06-15 13:20
Articles in Press
2021-06-15 13:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-07-07 01:37
Publish the Manuscript Online
2021-07-12 00:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?
Manuscript Source Invited Manuscript
All Author List Robert S O'Neill and Alina Stoita
ORCID
Author(s) ORCID Number
Robert S O'Neill http://orcid.org/0000-0002-9576-2248
Alina Stoita http://orcid.org/0000-0001-9460-2149
Funding Agency and Grant Number
Corresponding Author Alina Stoita, FRACP, MBBS, Doctor, Lecturer, Department of Gastroenterology, St Vincent's Hospital Sydney, 390 Victoria Street, Sydney 2010, Australia. alina.stoita@svha.org.au
Key Words Pancreatic cancer; Cancer; Biomarkers; Diagnostic; Review
Core Tip Circulating biomarkers are an attractive method for pancreatic cancer (PC) diagnosis. Over 300 biomarkers are presented in this review, however no gold standard biomarker exists. While carbohydrate antigen 19-9 possesses modest sensitivity in PC diagnosis, a lack of specificity is a limitation for its use. More recent studies have shifted towards the concept of a liquid biopsy along with measuring expression of RNA based markers in different mediums. Panels comprising multiple candidate biomarkers have emerged, demonstrating modest diagnostic value. Further studies are required to validate these findings, along with assessment in an asymptomatic population to determine their value in screening.
Publish Date 2021-07-12 00:42
Citation O'Neill RS, Stoita A. Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket? World J Gastroenterol 2021; 27(26): 4045-4087
URL https://www.wjgnet.com/1007-9327/full/v27/i26/4045.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i26.4045
Full Article (PDF) WJG-27-4045.pdf
Full Article (Word) WJG-27-4045.docx
Manuscript File 63224_Auto_Edited-ZMG.docx
Answering Reviewers 63224-Answering reviewers.pdf
Audio Core Tip 63224-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 63224-Conflict-of-interest statement.pdf
Copyright License Agreement 63224-Copyright license agreement.pdf
Peer-review Report 63224-Peer-review(s).pdf
Scientific Misconduct Check 63224-Bing-Wang JL-1.jpg
Scientific Misconduct Check 63224-Scientific misconduct check.pdf
Scientific Editor Work List 63224-Scientific editor work list.pdf