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Articles Published Processes
6/25/2021 9:46:23 AM | Browse: 665 | Download: 1339
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Received |
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2021-01-26 19:27 |
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Peer-Review Started |
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2021-01-26 19:37 |
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To Make the First Decision |
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Return for Revision |
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2021-02-24 06:35 |
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Revised |
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2021-03-13 14:40 |
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Second Decision |
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2021-05-25 14:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-25 15:06 |
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Articles in Press |
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2021-05-25 15:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-06-19 08:57 |
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Publish the Manuscript Online |
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2021-06-25 09:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Abhilash Perisetti, Hemant Goyal, Rachana Yendala, Ragesh B Thandassery and Emmanouil Giorgakis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Emmanouil Giorgakis, FRCS, MD, MSc, Assistant Professor, Department of Transplant, University of Arkansas for Medical Sciences Little Rock, 4301 W Markham St, Little Rock, AR 72205, United States. egiorgakis@uams.edu |
| Key Words |
Cirrhosis; Hepatic fibrosis; Non-alcoholic liver disease; Primary liver cancer; Hepatocellular carcinoma; Hepatoma; Liver cancer; Hepatitis B virus; Hepatitis C virus; Liver resection; Liver transplantation |
| Core Tip |
Non-cirrhotic hepatocellular carcinoma (HCC) accounts for 20% of reported HCCs. Such tumors are typically diagnosed late, compromising the outcome. The discovery of direct antivirals, loco-regional treatments and systemic novel immune-chemotherapies, along with advancements of complex hepatobiliary surgery, and the genesis of transplant oncology have revolutionized the management of these aggressive primary liver tumors. Coordinated care at tertiary high-volume HCC, preferably liver transplant centers, remains critical. It is time the stakeholders pursued a consensus approach in developing universal HCC surveillance and treatment strategies on non-cirrhotic patients at risk, such as patients with non-alcoholic steatohepatitis and/or patients with advanced fibrosis. |
| Publish Date |
2021-06-25 09:46 |
| Citation |
Perisetti A, Goyal H, Yendala R, Thandassery RB, Giorgakis E. Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements. World J Gastroenterol 2021; 27(24): 3466-3482 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i24/3466.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i24.3466 |
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