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7/6/2021 2:31:17 AM | Browse: 328 | Download: 728
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Received |
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2021-01-29 02:37 |
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Peer-Review Started |
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2021-01-29 02:48 |
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To Make the First Decision |
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Return for Revision |
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2021-02-25 04:55 |
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Revised |
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2021-03-11 08:27 |
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Second Decision |
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2021-06-04 09:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-06-04 10:04 |
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Articles in Press |
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2021-06-04 10:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-14 13:51 |
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Typeset the Manuscript |
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2021-06-30 02:01 |
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Publish the Manuscript Online |
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2021-07-06 02:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Diverse expression pattern of mucin 2 in colorectal cancer indicates its mechanism related to the intestinal mucosal barrier
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Guo-Lian Gan, Hua-Tao Wu, Wen-Jia Chen, Chun-Lan Li, Qian-Qian Ye, Yi-Feng Zheng and Jing Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81501539 |
| the Natural Science Foundation of Guangdong Province, China |
2016A030312008 |
| Science and Technology Planning Project of Shantou, China |
200617105260368 |
| Medical Scientific Research Foundation of Guangdong, China |
A2020627 |
| “Dengfeng Project” for the construction of high-level hospital in Guangdong Province—the First Affiliated Hospital of Shantou University College Supporting Funding |
202003-10 |
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| Corresponding Author |
Jing Liu, MD, PhD, Associate Professor, Changjiang Scholar’s Laboratory, Shantou University Medical College, No. 22 Xinling Road, Shantou 515041, Guangdong Province, China. jliu12@stu.edu.cn |
| Key Words |
Colorectal cancer; Mucin 2; Mucin; Expression; Intestinal mucosal barrier; Prognosis |
| Core Tip |
This study found that mucin 2 (MUC2) in intestinal tissues may play a protective role on the intestine and can be used as one of the indicators to evaluate the prognosis of patients with colorectal cancer (CRC). When the intestinal mucosal barrier function of patients with CRC is impaired, the serum level of MUC2 can reflect the severity of the damage. So, in CRC patients with impaired intestinal mucosal barrier function, the serum level of MUC2 could reflect the severity of the damage, providing a potential mechanism for the development of therapeutic strategies on CRC patients. |
| Publish Date |
2021-07-06 02:31 |
| Citation |
Gan GL, Wu HT, Chen WJ, Li CL, Ye QQ, Zheng YF, Liu J. Diverse expression pattern of mucin 2 in colorectal cancer indicates its mechanism related to the intestinal mucosal barrier. World J Gastroenterol 2021; 27(25): 3888-3900 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i25/3888.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i25.3888 |
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