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Articles Published Processes
8/28/2014 9:54:00 AM | Browse: 979 | Download: 957
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Received |
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2013-10-18 16:48 |
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Peer-Review Started |
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2013-10-22 10:26 |
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To Make the First Decision |
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2014-01-12 11:03 |
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Return for Revision |
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2014-01-12 13:27 |
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Revised |
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Second Decision |
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2014-03-06 18:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-06 18:05 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-09 15:31 |
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Typeset the Manuscript |
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2014-04-28 18:13 |
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Publish the Manuscript Online |
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2014-05-14 10:58 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Use of lectin microarray to differentiate gastric cancer from gastric ulcer
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Manuscript Source |
Invited Manuscript |
All Author List |
Wei-Li Huang, Yang-Guang Li, Yong-Chen Lv, Xiao-Hui Guan, Hui-Fan Ji and Bao-Rong Chi |
Funding Agency and Grant Number |
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Corresponding Author |
Bao-Rong Chi, MD, PhD, Professor, Department of Hepatology, the First Clinic Hospital of Jilin University, No. 71 Xinmin Dajie, Changchun 130021, Jilin Province, China. chibr@jlu.edu.cn |
Key Words |
Gastric cancer; Gastric ulcer; Lectin microarray; Lectin histochemistry; Differentiate |
Core Tip |
To assess the different glycopatterns in gastric ulcer and cancer by lectin microarray, which was then validated by lectin histochemistry. The results showed that the glycosylation level of gastric cancer was significantly higher than that in ulcer; the subsequent validation with two lectins (MPL and VVA) using lectin histochemistry showed higher positive rates and signal intensity in all types of gastric cancer detected, when compared with ulcer, which was consistent with the results of the lectin microarray, suggesting that GalNAc bound by the lectins MPL and VVA could be used to distinguish gastric cancer from ulcer. |
Publish Date |
2014-05-14 10:58 |
Citation |
Huang WL, Li YG, Lv YC, Guan XH, Ji HF, Chi BR. Use of lectin microarray to differentiate gastric cancer from gastric ulcer. World J Gastroenterol 2014; 20(18): 5474-5482 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i18/5474.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i18.5474 |
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