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7/10/2021 10:08:35 AM | Browse: 241 | Download: 376
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 63410
Country China
Received
2021-03-04 15:08
Peer-Review Started
2021-03-04 15:12
To Make the First Decision
Return for Revision
2021-04-17 13:51
Revised
2021-04-19 07:50
Second Decision
2021-06-01 12:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-06-01 13:19
Articles in Press
2021-06-01 13:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-08 01:24
Typeset the Manuscript
2021-07-08 14:45
Publish the Manuscript Online
2021-07-10 10:08
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions
Manuscript Source Invited Manuscript
All Author List Zhang-Ming Chen, Jie Hu, Yuan-Min Xu, Wei He, Lei Meng, Ting Huang, Song-Cheng Ying, Zhe Jiang and A-Man Xu
ORCID
Author(s) ORCID Number
Zhang-Ming Chen http://orcid.org/0000-0002-4830-0745
Jie Hu http://orcid.org/0000-0003-2293-8756
Yuan-Min Xu http://orcid.org/0000-0002-0499-3754
Wei He http://orcid.org/0000-0002-1489-6093
Lei Meng http://orcid.org/0000-0002-1089-1228
Ting Huang http://orcid.org/0000-0002-2623-373X
Song-Cheng Ying http://orcid.org/0000-0002-3446-4482
Zhe Jiang http://orcid.org/0000-0002-9042-1030
A-Man Xu http://orcid.org/0000-0001-5656-0646
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81572350
Corresponding Author A-Man Xu, MD, PhD, Professor, Department of General Surgery, Fourth Affiliated Hospital of Anhui Medical University, No. 100 Huaihai Avenue, Hefei 230001, Anhui Province, China. xamhwx@163.com
Key Words Cytotoxin associated gene A; SHP2; Cryptotanshinone; Helicobacter pylori; Chronic infection model
Core Tip Cryptotanshinone inhibited cytotoxin-associated gene A (CagA) induced proliferation and epithelial-mesenchymal transition of gastric cancer cells in vitro and Helicobacter pylori (H. pylori) CagA-positive strains caused mucosal erosions of stomach in vivo, throuth decreasing the expression of SHP2 protein, which could be an effective drug in treating H. pylori infection.
Publish Date 2021-07-10 10:08
Citation Chen ZM, Hu J, Xu YM, He W, Meng L, Huang T, Ying SC, Jiang Z, Xu AM. Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions. World J Gastrointest Oncol 2021; 13(7): 693-705
URL https://www.wjgnet.com/1948-5204/full/v13/i7/693.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i7.693
Full Article (PDF) WJGO-13-693.pdf
Full Article (Word) WJGO-13-693.docx
Manuscript File 63410-Review-FilipodiaCL .docx
Answering Reviewers 63410-Answering reviewers.pdf
Audio Core Tip 63410-Audio core tip.m4a
Biostatistics Review Certificate 63410-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 63410-Conflict-of-interest statement.pdf
Copyright License Agreement 63410-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 63410-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 63410-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 63410-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 63410-Language certificate.pdf
Peer-review Report 63410-Peer-review(s).pdf
Scientific Misconduct Check 63410-Bing-Wang JL-1.jpg
Scientific Misconduct Check 63410-Bing-Fan JR-2.png
Scientific Misconduct Check 63410-Scientific misconduct check.pdf
Scientific Editor Work List 63410-Scientific editor work list.pdf