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Articles Published Processes
8/4/2021 7:56:20 AM | Browse: 484 | Download: 1081
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Received |
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2021-01-29 00:31 |
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Peer-Review Started |
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2021-01-29 00:34 |
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To Make the First Decision |
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Return for Revision |
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2021-03-29 01:56 |
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Revised |
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2021-04-03 21:50 |
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Second Decision |
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2021-04-22 13:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-22 13:49 |
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Articles in Press |
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2021-04-22 13:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-05-03 01:12 |
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Typeset the Manuscript |
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2021-05-31 10:52 |
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Publish the Manuscript Online |
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2021-08-04 07:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Poor performance of anti-mitochondrial antibodies for the diagnosis of primary biliary cholangitis in female Colombian patients: A single-center study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Valentina Guatibonza-García, Paula Valentina Gaete, Agustín Pérez-Londoño, Danna Kathalina Puerto-Baracaldo, Sebastián Antonio Gutiérrez-Romero, Carlos O Mendivil and Monica Tapias |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Monica Tapias, MD, Attending Doctor, Department of Hepatology, Fundación Santa Fe de Bogotá, Carrera 7 No.117-15, Bogotá 110111, Colombia. monictapias@yahoo.com |
| Key Words |
Primary biliary cholangitis; Antibodies; Anti-mitochondrial antibodies; Latin America; Anti-smooth muscle antibodies |
| Core Tip |
Primary biliary cholangitis (PBC) is confirmed by liver biopsy, but autoantibodies are frequently employed as an indirect diagnostic method. We studied 85 female adult Latin American patients, 43 with biopsy-confirmed PBC and 42 in whom liver biopsy ruled out PBC. The prevalence of anti-mitochondrial antibodies among PBC cases was only 44.2%. Anti-nuclear antibodies and anti-smooth muscle antibodies had similarly low diagnostic performance. Eighty-two percent of immunoglobulin M-positive individuals had fibrosis in their biopsy. Among female Latin American patients with PBC, the performance of any individual antibody for PBC diagnosis was quite limited. |
| Publish Date |
2021-08-04 07:56 |
| Citation |
Guatibonza-García V, Gaete PV, Pérez-Londoño A, Puerto-Baracaldo DK, Gutiérrez-Romero SA, Mendivil CO, Tapias M. Poor performance of anti-mitochondrial antibodies for the diagnosis of primary biliary cholangitis in female Colombian patients: A single-center study. World J Gastroenterol 2021; 27(29): 4890-4899 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i29/4890.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i29.4890 |
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