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Articles Published Processes
7/12/2021 5:45:28 AM | Browse: 578 | Download: 822
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Received |
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2021-01-29 00:15 |
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Peer-Review Started |
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2021-01-29 00:18 |
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To Make the First Decision |
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Return for Revision |
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2021-03-16 06:35 |
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Revised |
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2021-03-21 16:50 |
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Second Decision |
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2021-04-29 09:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-04-29 11:34 |
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Articles in Press |
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2021-04-29 11:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-05-27 19:40 |
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Typeset the Manuscript |
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2021-06-15 02:28 |
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Publish the Manuscript Online |
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2021-07-12 05:45 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Field of Vision |
| Article Title |
Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Infante, Martina Leoni, Massimiliano Caprio and Andrea Fabbri |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Infante, MD, N/A, Adjunct Professor, UniCamillus, Saint Camillus International University of Health Sciences, Via di Sant’Alessandro 8, Rome 00131, Italy. marco.infante@unicamillus.org |
| Key Words |
Metformin; Vitamin B12 deficiency; Metformin-induced cobalamin deficiency; Diabetes; Type 2 diabetes; Prediabetes; Screening criteria; Neuropathy; Anemia |
| Core Tip |
Over the last decades, vitamin B12 deficiency has been increasingly recognized as a possible consequence of long-term metformin therapy, potentially resulting in clinical manifestations such as hematologic abnormalities and peripheral neuropathy. Metformin-induced vitamin B12 deficiency has relevant implications in light of the growing population of individuals on metformin therapy for the treatment of type 2 diabetes, prediabetes, insulin resistance and polycystic ovary syndrome on a global scale. Notwithstanding, no definite guidelines are currently available for vitamin B12 deficiency screening in metformin-treated patients. We therefore propose a list of criteria for a cost-effective vitamin B12 deficiency screening in metformin-treated patients. |
| Publish Date |
2021-07-12 05:45 |
| Citation |
Infante M, Leoni M, Caprio M, Fabbri A. Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind. World J Diabetes 2021; 12(7): 916-931 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i7/916.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i7.916 |
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