9/1/2014 12:00:00 PM | Browse: 1200 | Download: 1082
Publication Name | World Journal of Diabetes |
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Manuscript ID | 6359 |
Country | Sweden |
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2014-02-19 15:19 |
ISSN | 1948-9358 (online) |
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Open Access | |
Copyright | |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Endocrinology & Metabolism |
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Manuscript Type | Review |
Article Title | Insulin plus incretin: A glucose-lowering strategy for type 2-diabetes |
Manuscript Source | Invited Manuscript |
All Author List | Bo Ahrén |
Funding Agency and Grant Number | |
Corresponding Author | Dr. Bo Ahrén, Professor, Department of Clinical Sciences Lund, Lund University, B11 BMC, 221 84 Lund, Sweden. bo.ahren@med.lu.se |
Key Words | Type 2 diabetes; Glucose lowering; Insulin therapy; Glucagon-like peptide-1 receptor agonists; Dipeptidyl peptidase-4 inhibitors; Incretin therapy; Combination |
Core Tip | Incretin therapy (glucagon-like peptide-1 receptor agonists or dipeptidyl peptidase-4 inhibitors) combined with insulin therapy is a glucose-lowering strategy in type 2 diabetes. The combination allows a complementary mode of mechanistic action and, as demonstrated in several clinical trials, is glucose-lowering in association with limited risk for hypoglycemia and weight gain. The combination is a promising strategy in patients in whom metformin with either incretin therapy or basal insulin is insufficient for adequate glycemic control. This article reviews the background and clinical studies on this combination. |
Publish Date | 2014-02-19 15:19 |
Citation | Ahrén B. Insulin plus incretin: A glucose-lowering strategy for type 2-diabetes. World J Diabetes 2014; 5(1): 40-51 Available from: URL: http://www.wjgnet.com/1948-9358/full/v5/i1/40.htm DOI: http://dx.doi.org/10.4239/wjd.v5.i1.40 |
URL | http://www.wjgnet.com/1948-9358/full/v5/i1/40.htm |
DOI | http://dx.doi.org/10.4239/wjd.v5.i1.40 |
Full Article (PDF) | WJD-5-40.pdf |
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Full Article (Word) | WJD-5-40.doc |
Manuscript File | 6359-Review.docx |
Answering Reviewers | 6359-Answering reviewers.pdf |
Copyright License Agreement | 6359-Copyright assignment.pdf |
Peer-review Report | 6359-Peer review(s).pdf |
Scientific Editor Work List | 6359-Scientific editor work list.doc |