BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/12/2021 10:20:44 PM | Browse: 913 | Download: 1892
 |
Received |
|
2021-02-01 16:41 |
|
Peer-Review Started |
|
2021-02-01 16:51 |
|
First Decision by Editorial Office Director |
|
2021-03-08 06:40 |
|
Return for Revision |
|
2021-03-08 06:40 |
|
Revised |
|
2021-03-17 17:07 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2021-05-24 12:14 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2021-05-24 12:45 |
|
Articles in Press |
|
2021-05-24 12:45 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2021-06-04 08:00 |
|
Publish the Manuscript Online |
|
2021-06-12 22:20 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Liver transplantation in acute liver failure: Dilemmas and challenges
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ramesh Kumar, Utpal Anand and Rajeev Nayan Priyadarshi |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Ramesh Kumar, MD, Associate Professor, Department of Gastroenterology, All India Institute of Medical Sciences, Phulwari Sharif, Patna 801507, Bihar, India. docrameshkr@gmail.com |
| Key Words |
Acute liver failure; Fulminant hepatic failure; Prognosis; Kings college criteria; Liver transplantation; Acetaminophen |
| Core Tip |
Liver transplantation (LT) is a lifesaving procedure for patients with acute liver failure (ALF). Its use, however, is constrained by the absence of reliable prognostic models that hampers the selection of transplant candidates in a timely and precise manner. The survival of medically treated ALF patients has increased over time, but the criteria for LT remain the same. No clear advantage of LT in acetaminophen-associated ALF appears to be present. The other problems associated with LT in ALF are diagnostic dilemmas, shortage of graft, waiting list contraindications, vaguely defined delisting criteria, pre-transplant assessment time limits, ethical concerns, and comparatively poor post-transplant outcomes. Therefore, there is a desperate need to establish accurate prognostic models and explore the roles of alternative therapies to enhance transplant-free survival and fill the gap produced by the shortage of graft. |
| Publish Date |
2021-06-12 22:20 |
| Citation |
Kumar R, Anand U, Priyadarshi RN. Liver transplantation in acute liver failure: Dilemmas and challenges. World J Transplant 2021; 11(6): 187-202 |
| URL |
https://www.wjgnet.com/2220-3230/full/v11/i6/187.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v11.i6.187 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
