Publication Name	World Journal of Clinical Oncology
Manuscript ID	63749
Country	Mexico

Received	2021-02-01 21:34
Peer-Review Started	2021-02-01 21:45
To Make the First Decision
Return for Revision	2021-03-31 05:00
Revised	2021-04-07 23:49
Second Decision	2021-07-27 03:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-07-27 06:42
Articles in Press	2021-07-27 06:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-08-20 02:53
Publish the Manuscript Online	2021-08-23 06:43

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	TRIM25: A central factor in breast cancer
Manuscript Source	Invited Manuscript
All Author List	Angeles C Tecalco-Cruz, María Jazmin Abraham-Juárez, Helena Solleiro-Villavicencio and Josué Orlando Ramírez-Jarquín
ORCID	Author(s) ORCID Number Angeles C Tecalco-Cruz http://orcid.org/0000-0001-9199-3834 María Jazmin Abraham-Juárez http://orcid.org/0000-0002-5468-8176 Helena Solleiro-Villavicencio http://orcid.org/0000-0001-5137-3681 Josué Orlando Ramírez-Jarquín http://orcid.org/0000-0001-7574-8724
Funding Agency and Grant Number
Corresponding Author	Angeles C Tecalco-Cruz, PhD, Full Professor, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México (UACM), Colonia Del valle, San Lorenzo 290, Mexico 03100, Mexico. angeles.tecalco@uacm.edu.mx
Key Words	TRIM25; Interferon-stimulated gene 15; Ubiquitin; Estrogens; Breast cancer
Core Tip	TRIM25 is an E3-ligase enzyme for the ubiquitination and ISGylation system. TRIM25 expression is deregulated in breast cancer. The activity of TRIM25 is associated with changes in the proteome of mammary tumors. The molecular mechanisms of modulation and action of TRIM25 are implicated in breast cancer progression.
Publish Date	2021-08-23 06:43
Citation	Tecalco-Cruz AC, Abraham-Juárez MJ, Solleiro-Villavicencio H, Ramírez-Jarquín JO. TRIM25: A central factor in breast cancer. World J Clin Oncol 2021; 12(8): 646-655
URL	https://www.wjgnet.com/2218-4333/full/v12/i8/646.htm
DOI	https://dx.doi.org/10.5306/wjco.v12.i8.646

Full Article (PDF)	WJCO-12-646.pdf
Full Article (Word)	WJCO-12-646.docx
Manuscript File	63749_Auto_Edited-JPY.docx
Answering Reviewers	63749-Answering reviewers.pdf
Audio Core Tip	63749-Audio core tip.wma
Conflict-of-Interest Disclosure Form	63749-Conflict-of-interest statement.pdf
Copyright License Agreement	63749-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	63749-Language certificate.pdf
Peer-review Report	63749-Peer-review(s).pdf
Scientific Misconduct Check	63749-Bing-Wu YXJ-2.jpg
Scientific Misconduct Check	63749-Scientific misconduct check.pdf
Scientific Editor Work List	63749-Scientific editor work list.pdf
CrossCheck Report	63749-CrossCheck report.pdf