Publication Name	World Journal of Gastroenterology
Manuscript ID	6377
Country	China

Received	2013-10-15 15:00
Peer-Review Started	2013-10-16 14:11
To Make the First Decision	2013-12-16 17:46
Return for Revision	2013-12-18 10:12
Revised	2013-12-31 10:31
Second Decision	2014-04-09 08:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-09 08:51
Articles in Press	2014-05-23 11:08
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-01 19:02
Typeset the Manuscript	2014-06-25 15:15
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Changes in circulating Foxp3+ regulatory T cells and interleukin-17-producing T helper cells during HBV-related acute-on-chronic liver failure
Manuscript Source	Invited Manuscript
All Author List	Xue-Song Liang, Cheng-Zhong Li, Yin Zhou, Wei Yin, Ya-Yun Liu and Wen-Han Fan
Funding Agency and Grant Number	Funding Agency Grant Number Shanghai Natural Science Fund 09ZR1400500 National Natural Science Foundation of China 30972600 Shanghai Health Bureau Fund 2012092
Corresponding Author	Xue-Song Liang, Associate Professor, Department of Infectious Diseases, Changhai Hospital, Second Military Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433, China. liangxuesong2000@163.com
Key Words	Hepatitis B virus; Treg; Th17; Immune; Hepatitis B virus-related acute-on-chronic liver failure
Core Tip	In this study, we longitudinally investigated Foxp3+Treg cells and IL-17+Th cells by measuring gene levels, protein levels and T-cell phenotypes during HBV-related acute-on-chronic liver failure (ACHBLF) progression. From the onset of ACHBLF, there were changes in Foxp3+Treg and Th17 cell frequencies. An increased Treg/Th17 ratio was associated with the survival of ACHBLF patients.
Publish Date	2014-07-14 17:39
Citation	Liang XS, Li CZ, Zhou Y, Yin W, Liu YY, Fan WH. Changes in circulating Foxp3+ regulatory T cells and interleukin-17-producing T helper cells during HBV-related acute-on-chronic liver failure. World J Gastroenterol 2014; 20(26): 8558-8571
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8558.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8558

Full Article (PDF)	WJG-20-8558.pdf
Full Article (Word)	WJG-20-8558.doc
Manuscript File	6377-Review.docx
Answering Reviewers	6377-Answering reviewers.pdf
Copyright License Agreement	6377-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20131015014234.jpg
Non-Native Speakers of English Editing Certificate	6377-Language certificate.pdf
Peer-review Report	6377-Peer review(s).pdf
Scientific Editor Work List	6377-Scientific editor work list.doc