Publication Name	World Journal of Clinical Cases
Manuscript ID	63780
Country	China

Received	2021-02-02 12:16
Peer-Review Started	2021-02-02 12:21
To Make the First Decision
Return for Revision	2021-04-06 13:52
Revised	2021-04-17 18:37
Second Decision	2021-07-02 12:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-02 13:31
Articles in Press	2021-07-02 13:31
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-12 14:14
Typeset the Manuscript	2021-07-30 02:33
Publish the Manuscript Online	2021-08-05 14:37

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Novel mechanism of hepatobiliary system damage and immunoglobulins G4 elevation caused by Clonorchis sinensis infection
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-He Zhang, Die Huang, Yi-Ling Li and Bing Chang
ORCID	Author(s) ORCID Number Xin-He Zhang http://orcid.org/0000-0002-8773-2647 Die Huang http://orcid.org/0000-0003-0922-3473 Yi-Ling Li http://orcid.org/0000-0003-8209-8105 Bing Chang http://orcid.org/0000-0003-1965-5827
Funding Agency and Grant Number
Corresponding Author	Bing Chang, PhD, Assistant Professor, Department of Gastroenterology, The First Affiliated Hospital of China Medical University, No. 155 North Nanjing Street, Heping District, Shenyang 110001, Liaoning Province, China. cb000216@163.com
Key Words	Liver damage; Bile duct damage; Hepatobiliary system destruction; Clonorchis sinensis infection; Immunoglobulins G4; Clinical manifestations
Core Tip	The increase in immunoglobulins G4 (IgG4) caused by Clonorchis sinensis infection is rare and there are few reports about mechanism. We report novel mechanisms of IgG4 elevation due to Clonorchis sinensis infection to provide more experience and a theoretical basis for clinical diagnosis and treatment.
Publish Date	2021-08-05 14:37
Citation	Zhang XH, Huang D, Li YL, Chang B. Novel mechanism of hepatobiliary system damage and immunoglobulins G4 elevation caused by Clonorchis sinensis infection. World J Clin Cases 2021; 9(23): 6639-6653
URL	https://www.wjgnet.com/2307-8960/full/v9/i23/6639.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i23.6639

Full Article (PDF)	WJCC-9-6639.pdf
Full Article (Word)	WJCC-9-6639.docx
Manuscript File	63780_Auto_Edited-ZMG_WangTQ.docx
Answering Reviewers	63780-Answering reviewers.pdf
Audio Core Tip	63780-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	63780-Conflict-of-interest statement.pdf
Copyright License Agreement	63780-copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	63780-Language certificate.pdf
Peer-review Report	63780-Peer-review(s).pdf
Scientific Misconduct Check	63780-Bing-Ma YJ-1.jpg
Scientific Misconduct Check	63780-Bing-Fan JR-2.png
Scientific Misconduct Check	63780-Scientific misconduct check.pdf
Scientific Editor Work List	63780-Scientific editor work list.pdf