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Articles Published Processes
3/3/2022 6:59:41 AM | Browse: 519 | Download: 984
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Received |
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2021-02-04 18:08 |
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Peer-Review Started |
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2021-02-04 18:16 |
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To Make the First Decision |
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Return for Revision |
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2021-07-27 23:53 |
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Revised |
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2021-08-09 18:22 |
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Second Decision |
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2022-01-27 03:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-29 06:57 |
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Articles in Press |
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2022-01-29 06:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-01-25 02:09 |
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Typeset the Manuscript |
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2022-02-22 07:29 |
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Publish the Manuscript Online |
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2022-03-03 06:59 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Innate and adaptive immune escape mechanisms of hepatitis B virus
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hua-Jun Zhao, Yi-Fei Hu, Qiu-Ju Han and Jian Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science Foundation for Young Scientists of China |
82001687 |
| National Major Science and Technology Project for Control and Prevention of Major Infectious Diseases |
2018ZX10301401 |
| National Postdoctoral Program for Innovative Talents |
BX20190192 |
| China Postdoctoral Science Foundation |
2020M672064 |
| National Basic Research Program of China |
2013CB531503 |
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| Corresponding Author |
Jian Zhang, PhD, Professor, Institute of Immunopharmaceutical Sciences, School of Pharmaceutical Sciences , Shandong University, 44 Wenhua West Road, Jinan 250012, Shandong Province, China. zhangj65@sdu.edu.cn |
| Key Words |
Hepatitis B virus; Innate immunity; Adaptive immunity; Immune tolerance; Therapeutic strategy |
| Core Tip |
Chronic hepatitis B (CHB) infection is an international health problem. Current clinical CHB treatment strategies can partly inhibit and eliminate hepatitis B virus (HBV), but cannot achieve long-lasting immune control of the virus. Persistent CHB infection arises as a consequence of the complex interactions between HBV and the host innate and adaptive immune systems. Therefore, it is important to understand the immunological mechanisms involved in CHB infection. In this review, we detail the immune biological characteristics and escape mechanisms of HBV and discuss novel immune-based therapies. |
| Publish Date |
2022-03-03 06:59 |
| Citation |
Zhao HJ, Hu YF, Han QJ, Zhang J. Innate and adaptive immune escape mechanisms of hepatitis B virus. World J Gastroenterol 2022; 28(9): 881-896 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i9/881.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i9.881 |
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