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        9/6/2021 12:41:27 AM | Browse: 667 | Download: 1321
    
    
        
        
    
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                    |  | Received |  | 2021-02-05 18:05 | 
    
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                    |  | Peer-Review Started |  | 2021-02-05 18:12 | 
    
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                    |  | To Make the First Decision |  |  | 
    
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                    |  | Return for Revision |  | 2021-03-31 04:01 | 
    
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                    |  | Revised |  | 2021-04-23 14:08 | 
    
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                    |  | Second Decision |  | 2021-08-24 03:23 | 
    
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                    |  | Accepted by Journal Editor-in-Chief |  |  | 
    
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                    |  | Accepted by Executive Editor-in-Chief |  | 2021-08-24 07:48 | 
    
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                    |  | Articles in Press |  | 2021-08-24 07:48 | 
    
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                    |  | Publication Fee Transferred |  |  | 
    
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                    |  | Edit the Manuscript by Language Editor |  |  | 
    
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                    |  | Typeset the Manuscript |  | 2021-09-02 07:38 | 
            
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                            |  | Publish the Manuscript Online |  | 2021-09-06 00:41 | 
        
        
            
                | ISSN | 2219-2808 (online) | 
            
                | Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ | 
            
                | Copyright | ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. | 
                    
                        | Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 | 
            
            
                | Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 | 
            
            
                | Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | 
            
                | Website | http://www.wjgnet.com | 
        
    
        | Category | Pediatrics | 
    
        | Manuscript Type | Minireviews | 
    
        | Article Title | Prospects for clinical applications of butyrate-producing bacteria | 
    
        | Manuscript Source | Invited Manuscript | 
    
        | All Author List | Li-Bin Zhu, Yu-Chen Zhang, Han-Hui Huang and Jing Lin | 
            
                | ORCID |  | 
    
        | Funding Agency and Grant Number | 
                        
                            
                                | Funding Agency | Grant Number |  
                                        | Medical and Health Science and Technology Plan of Zhejiang Province | 2018KY128 |  | 
    
        | Corresponding Author | Jing Lin, MD, Associate Professor, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, United States. jing.lin@mssm.edu | 
    
        | Key Words | Butyrate; Butyrate-producing bacteria; Gut microbiota; Intestinal mucosal barrier; Metabolic syndrome; Probiotics | 
    
        | Core Tip | This minireview summarizes the potential clinical applications of butyrate-producing bacteria in disorders related to pediatrics and possible underlying mechanisms. Acting as probiotics, butyrate-producing bacteria play important roles in a variety of normal biological functions that include balancing gut microbiota, maintaining the mucosal barrier, modulating the host immune response, preventing infections, and regulating energy expenditure. Therefore, butyrate-producing bacteria may have a potential therapeutic value in a wide range of clinical conditions associated with intestinal dysbiosis such as inflammatory bowel disease, necrotizing enterocolitis, late-onset sepsis in the premature infant, nosocomial diarrhea, and obesity-associated metabolic disorders. | 
            
                | Publish Date | 2021-09-06 00:41 | 
    
        | Citation | Zhu LB, Zhang YC, Huang HH, Lin J. Prospects for clinical applications of butyrate-producing bacteria. World J Clin Pediatr 2021; 10(5): 84-92 | 
            
                | URL | https://www.wjgnet.com/2219-2808/full/v10/i5/84.htm | 
            
                | DOI | https://dx.doi.org/10.5409/wjcp.v10.i5.84 | 
    
    
        
                
        
     
 
                 
             
         
        
    
        
        
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