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Articles Published Processes
9/10/2021 12:09:57 PM | Browse: 517 | Download: 1215
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Received |
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2021-02-06 18:57 |
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Peer-Review Started |
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2021-02-06 19:05 |
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To Make the First Decision |
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Return for Revision |
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2021-05-08 04:23 |
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Revised |
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2021-06-01 14:53 |
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Second Decision |
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2021-07-19 03:18 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-19 08:51 |
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Articles in Press |
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2021-07-19 08:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-28 01:12 |
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Typeset the Manuscript |
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2021-09-03 00:42 |
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Publish the Manuscript Online |
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2021-09-10 12:09 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Neoadjuvant chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pei Wu, Hui-Mian Xu and Zhi Zhu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81302129 |
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| Corresponding Author |
Zhi Zhu, PhD, Doctor, Doctor, Department of Surgical Oncology, The First Hospital of China Medical University, No. 155 Nanjing Street, Shenyang 110001, Liaoning Province, China. zhuzhi@cmu.edu.cn |
| Key Words |
Rectal cancer; Neoadjuvant chemotherapy; Chemoradiation; Prognosis |
| Core Tip |
Neoadjuvant chemoradiotherapy (Neo-CRT) acts as standard treatment in locally advanced rectal cancer (LARC), however, it delays the administration of optimal chemotherapy and increases toxicity. We design the meta-analysis aimed to compare the feasibility and efficacy of neoadjuvant chemotherapy (Neo-CT) vs Neo-CRT for the treatment of LARC. The present study showed that Neo-CT was effective for the treatment of LARC, especially to lower the incidences of anastomotic fistula and temporary colostomy, and increase the sphincter preservation rate as compared to Neo-CRT, and could have the potential to provide an alternative to chemoradiotherapy for LARC. |
| Publish Date |
2021-09-10 12:09 |
| Citation |
Wu P, Xu HM, Zhu Z. Neoadjuvant Chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis. World J Gastrointest Oncol 2021; 13(9): 1196-1209 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i9/1196.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i9.1196 |
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