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Articles Published Processes
8/20/2021 10:31:42 AM | Browse: 708 | Download: 1517
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Received |
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2021-02-12 12:24 |
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Peer-Review Started |
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2021-02-12 12:28 |
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First Decision by Editorial Office Director |
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2021-05-04 01:32 |
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Return for Revision |
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2021-05-04 01:32 |
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Revised |
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2021-05-12 20:16 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2021-07-05 12:51 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-07-05 13:36 |
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Articles in Press |
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2021-07-05 13:36 |
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Edit the Manuscript by Language Editor |
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2021-07-16 07:25 |
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Typeset the Manuscript |
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2021-08-18 02:17 |
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Publish the Manuscript Online |
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2021-08-20 10:31 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Persistent bowel dysfunction after surgery for Hirschsprung’s disease: A neuropathological perspective
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sanne J Verkuijl, Florian Friedmacher, Patrick N Harter, Udo Rolle and Paul MA Broens |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sanne J Verkuijl, BSc, Research Fellow, Department of Pediatric Surgery, University Hospital Frankfurt, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, Germany. s.j.verkuijl@umcg.nl |
| Key Words |
Hirschsprung disease; Aganglionosis; Proximal; Ganglionic; Constipation; Incontinence |
| Core Tip |
Hirschsprung’s disease (HD) is a congenital disorder, characterized by aganglionosis in the distal part of the gastrointestinal tract. Despite surgical resection of the aganglionic bowel segment, bowel dysfunction persists in a considerable number of patients with limited treatment options. There is growing evidence regarding structural abnormalities in the proximal, ganglionic colon of both humans and animals with HD, which may play a role in the persisting bowel dysfunction. Hence, understanding of these previously unrecognized neuropathological abnormalities in the proximal, ganglionic bowel of patients with HD may improve current follow-up and treatment of persisting postoperative bowel dysfunction in certain patients. |
| Publish Date |
2021-08-20 10:31 |
| Citation |
Verkuijl SJ, Friedmacher F, Harter PN, Rolle U, Broens PM. Persistent bowel dysfunction after surgery for Hirschsprung’s disease: A neuropathological perspective. World J Gastrointest Surg 2021; 13(8): 822-833 |
| URL |
https://www.wjgnet.com/1948-9366/full/v13/i8/822.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v13.i8.822 |
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