Publication Name	World Journal of Gastroenterology
Manuscript ID	6423
Country	Germany

Received	2013-10-18 08:12
Peer-Review Started	2013-10-18 16:23
To Make the First Decision	2013-11-21 20:53
Return for Revision	2013-11-22 16:31
Revised	2013-11-28 18:08
Second Decision	2014-01-02 10:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-02 12:04
Articles in Press	2014-05-23 12:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-28 09:24
Publish the Manuscript Online	2014-06-21 13:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Molecular identification of hepatitis B virus genotypes/subgenotypes: Revised classification hurdles and updated resolutions
Manuscript Source	Invited Manuscript
All Author List	Mahmoud Reza Pourkarim, Samad Amini-Bavil-Olyaee, Fuat Kurbanov, Marc Van Ranst and Frank Tacke
Funding Agency and Grant Number	Funding Agency Grant Number ''Fonds voor Wetenschappelijk Onderzoek Vlaanderen''
Corresponding Author	Frank Tacke, MD, PhD, Department of Medicine Ⅲ, RWTH University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. frank.tacke@gmx.net
Key Words	Hepatitis B virus; Hepatitis; Classification; Genotype; Subgenotype; Phylogenetic tree
Core Tip	Hepatitis B virus (HBV) eradication could be achieved through three important points: (1) efficient universal vaccination; (2) accurate diagnostic assays; and (3) effective treatment of HBV carriers. Undoubtedly, these critical measures are not possible without fully understanding the genetics of the virus and being able to differentiate the isolates. In this review article we provide an update of HBV virology, focusing on classification and its impact on diagnosis, clinical outcomes, therapy, prophylaxis, evolution and epidemiology. Subsequently, the role of correct classification in describing HBV is highlighted, and misclassifications together with their causes are recounted. Finally, through the proposal of novel terms, HBV strains are reclassified.
Publish Date	2014-06-21 13:56
Citation	Pourkarim MR, Amini-Bavil-Olyaee S, Kurbanov F, Van Ranst M, Tacke F. Molecular identification of hepatitis B virus genotypes/subgenotypes: Revised classification hurdles and updated resolutions. World J Gastroenterol 2014; 20(23): 7152-7168
URL	http://www.wjgnet.com/1007-9327/full/v20/i23/7152.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i23.7152

Full Article (PDF)	WJG-20-7152.pdf
Full Article (Word)	WJG-20-7152.doc
Manuscript File	6423-Review.docx
Answering Reviewers	6423-Answering reviewers.pdf
Copyright License Agreement	6423-Copyright assignment.pdf
Peer-review Report	6423-Peer review(s).pdf
Scientific Editor Work List	6423-Scientific editor work list.doc