| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Xia Jiang, Tatsuo Kanda, Shuang Wu, Masato Nakamura, Tatsuo Miyamura, Shingo Nakamoto, Arup Banerjee and Osamu Yokosuka |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| “Asia-Oceania Collaborative Research Grants” from Kanae Foundation for the Promotion of Medical Science |
to Kanda T |
| Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology, Japan |
to Kanda T |
|
| Corresponding Author |
Tatsuo Kanda, MD, PhD, Associate Professor, Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. kandat-cib@umin.ac.jp |
| Key Words |
Hepatitis B virus; HepG2.2.15; Innate immunity; MicroRNA; Persistent infection; Toll-like receptor |
| Core Tip |
Hepatitis B virus (HBV) is the leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the world. HBV could interact with the host’s innate and adaptive immune responses to establish chronic infection. HBV also interacts with Toll-like receptors (TLRs) and TLR signaling pathways, and regulates host immune responses through the regulation of microRNAs (miRNAs) to some extent. This article focuses on the involvement of miRNA in the association between HBV and TLR signaling pathways and reviews the miRNAs involved in HBV infection. |
| Publish Date |
2014-06-21 13:56 |
| Citation |
Jiang X, Kanda T, Wu S, Nakamura M, Miyamura T, Nakamoto S, Banerjee A, Yokosuka O. Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity. World J Gastroenterol 2014; 20(23): 7197-7206 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i23/7197.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i23.7197 |
