ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Meta-Analysis |
Article Title |
Neoadjuvant chemotherapy for patients with resectable colorectal cancer liver metastases: A systematic review and meta-analysis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Yue Zhang, Long Ge, Jun Weng, Wen-Yu Tuo, Bin Liu, Shi-Xun Ma, Ke-Hu Yang and Hui Cai |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Key Research and Development Program Task Book |
2018YFC1311506 |
Natural Science Foundation of Gansu Province, China |
18JR3RA052 |
Lanzhou Talent Innovation and Entrepreneurship Project Task Contract |
2016-RC-56 |
Gansu Province Da Vinci Robot High End Diagnosis and Treatment Personnel Training Project |
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Corresponding Author |
Hui Cai, MD, PhD, Chief Doctor, Professor, Surgical Oncologist, General Surgery Clinical Medical Center, Gansu Provincial Hospital, No. 204 Donggang West Road, Lanzhou 730000, Gansu, China. caialonteam@163.com |
Key Words |
Colorectal neoplasm; Neoadjuvant chemotherapy; Systematic review; Randomized controlled trials; Meta-analysis; Colorectal liver metastases |
Core Tip |
Although hepatectomy is currently recommended as the most reliable treatment for colorectal liver metastasis, there are still a great number of patients who have recurrences and metastases after surgical resection. In recent years, neoadjuvant chemotherapy (NAC) has been increasingly used in patients with resectable colorectal liver metastases (CRLM). However, the efficacy and safety of NAC in the treatment of CRLM are still controversial. Therefore, we conducted a systematic review and meta-analysis to assess the value of NAC in patients with CRLM. |
Publish Date |
2021-07-28 01:52 |
Citation |
Zhang Y, Ge L, Weng J, Tuo WY, Liu B, Ma SX, Yang KH, Cai H. Neoadjuvant chemotherapy for patients with resectable colorectal cancer liver metastases. World J Clin Cases 2021; 9(22): 6357-6379 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i22/6357.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i22.6357 |