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Articles Published Processes
10/13/2021 12:57:54 PM | Browse: 573 | Download: 988
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Received |
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2021-02-16 18:20 |
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Peer-Review Started |
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2021-02-16 18:24 |
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To Make the First Decision |
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Return for Revision |
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2021-03-29 21:19 |
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Revised |
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2021-04-06 21:15 |
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Second Decision |
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2021-08-02 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-02 07:42 |
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Articles in Press |
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2021-08-02 07:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-15 23:59 |
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Typeset the Manuscript |
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2021-09-30 08:32 |
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Publish the Manuscript Online |
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2021-10-13 12:57 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Role of autophagy in gastric carcinogenesis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Apostolis Papaefthymiou, Gregory Christodoulidis, Apostolos Koffas, Michael Doulberis, Stergios A Polyzos, Anastasios Manolakis, Spyros Potamianos, Andreas Kapsoritakis and Jannis Kountouras |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Apostolis Papaefthymiou, MD, PhD, N/A, N/A, Department of Gastroenterology, University Hospital of Larissa, Mezourlo, Larissa 41110, Thessaly, Greece. appapaef@hotmail.com |
| Key Words |
Gastric cancer; Autophagy; Helicobacter pylori; Chemoresistance; Prognosis |
| Core Tip |
Autophagy comprises a substantial normal cellular function, implicated in benign and malignant diseases. Its complex regulatory system can be affected at any stage by endogenous and environmental factors. Helicobacter pylori expresses and stimulates a wide range of autophagy modulators, thus promoting or inhibiting autophagy to yield a survival benefit and cause damage. Concerning gastric cancer, the dysregulated autophagic process facilitates tumor generation, progress and resistance to chemotherapy, through various mechanisms. The current review attempts to decrypt and simplify those mechanisms and the respective pathways, to explain their promising potential for the development of therapeutic agents and prognostic tools. |
| Publish Date |
2021-10-13 12:57 |
| Citation |
Papaefthymiou A, Christodoulidis G, Koffas A, Doulberis M, Polyzos SA, Manolakis A, Potamianos S, Kapsoritakis A, Kountouras J. Role of autophagy in gastric carcinogenesis. World J Gastrointest Oncol 2021; 13(10): 1244-1262 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i10/1244.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i10.1244 |
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