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Articles Published Processes
8/31/2021 6:51:26 AM | Browse: 432 | Download: 624
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Received |
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2021-02-18 13:21 |
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Peer-Review Started |
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2021-02-18 13:24 |
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To Make the First Decision |
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Return for Revision |
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2021-04-18 07:35 |
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Revised |
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2021-04-24 12:26 |
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Second Decision |
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2021-07-19 03:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-19 05:05 |
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Articles in Press |
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2021-07-19 05:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-26 02:40 |
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Typeset the Manuscript |
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2021-08-24 01:36 |
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Publish the Manuscript Online |
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2021-08-31 06:51 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Is the simultaneous presence of IgG4-positive plasma cells and giant-cell hepatitis a coincidence in autoimmune hepatitis? A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
You-Wen Tan, Jia-Min Wang and Li Chen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
You-Wen Tan, MD, Chief Doctor, Professor, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, No. 300 Danjiamen, Runzhou District, Zhenjiang 212003, Jiangsu Province, China. tyw915@sina.com |
| Key Words |
IgG4; Autoimmune hepatitis; Giant-cell hepatitis; Case report |
| Core Tip |
A 68-year-old woman was hospitalized for liver function tests. Her immunological indices differed significantly from normal, and were accompanied by elevated serum IgG4 levels. Liver pathology revealed severe inflammation at the interface between portal tract and hepatocytes, plasma cell infiltration, formation of rosette cells, IgG4-positive plasma cells > 10/high-power field, IgG4/IgG > 40%, and multinucleated liver cell swelling. The patient was diagnosed as having IgG4-autoimmune hepatitis combined with giant-cell hepatitis (GCH), and 40 mg/day methylprednisolone was administered. A second liver biopsy 48 wk later indicated significant amelioration of liver inflammation and fibrosis. IgG4-positive plasma cells and GCHs were not detected. A literature search was conducted to analyze reports of similar pathological phenomena. |
| Publish Date |
2021-08-31 06:51 |
| Citation |
Tan YW, Wang JM, Chen L. Is the simultaneous presence of IgG4-positive plasma cells and giant-cell hepatitis a coincidence in autoimmune hepatitis? A case report. World J Clin Cases 2021; 9(25): 7527-7534 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i25/7527.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i25.7527 |
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