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Articles Published Processes
8/20/2021 5:46:25 AM | Browse: 484 | Download: 905
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Received |
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2021-02-18 23:32 |
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Peer-Review Started |
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2021-02-18 23:32 |
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To Make the First Decision |
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Return for Revision |
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2021-03-30 00:04 |
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Revised |
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2021-04-19 18:35 |
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Second Decision |
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2021-07-05 12:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-05 14:16 |
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Articles in Press |
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2021-07-05 14:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-17 17:56 |
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Typeset the Manuscript |
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2021-08-19 01:57 |
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Publish the Manuscript Online |
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2021-08-20 05:46 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Induced pluripotent stem cells as suitable sensors for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome
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| Manuscript Source |
Invited Manuscript |
| All Author List |
María B Monzón-Nomdedeu, Karl J Morten and Elisa Oltra |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Elisa Oltra, PhD, Full Professor, Department of Pathology, Universidad Católica de Valencia San Vicente Mártir, C/Quevedo 2, Valencia 46001, Spain, Spain. elisa.oltra@ucv.es |
| Key Words |
Myalgic encephalomyelitis/chronic fatigue syndrome; Fibromyalgia; Induced pluripotent stem cells; Plasma factor; Conditioned medium; Sensor system |
| Core Tip |
Based on the special environmental cue sensing abilities induced pluripotent stem cells (iPSCs) we are proposing their utility as suitable sensoring systems for metabolic disease. As fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome body-fluids show unique metabolic profiles, the applicability of iPSC-based bioassays for these conditions are worth investigating. We envisage the development of iPSC platforms which allow differential diagnosis and disease-specific high through put drug-screening platforms. Using healthy iPSCs and patient body fluids has significant advantages over using cell lines, patient primary cells or iPSC’s derived from patients. A consistent iPSC’s control line platform will provide a robust metabolic/phenotypic model allowing faster, cost-effective, large cohort screenings. |
| Publish Date |
2021-08-20 05:46 |
| Citation |
Monzón-Nomdedeu MB, Morten KJ, Oltra E. Induced pluripotent stem cells as suitable sensors for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome. World J Stem Cells 2021; 13(8): 1134-1150 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i8/1134.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i8.1134 |
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