Publication Name	World Journal of Critical Care Medicine
Manuscript ID	64665
Country	United States

Received	2021-02-21 22:12
Peer-Review Started	2021-02-21 22:22
To Make the First Decision
Return for Revision	2021-05-06 00:54
Revised	2021-05-16 13:18
Second Decision	2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-07-29 05:40
Articles in Press	2021-07-29 05:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-08-30 06:55
Publish the Manuscript Online	2021-09-09 09:23

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Role of proning and positive end-expiratory pressure in COVID-19
Manuscript Source	Invited Manuscript
All Author List	Kejal D Gandhi, Munish Sharma, Pahnwat Tonya Taweesedt and Salim Surani
ORCID	Author(s) ORCID Number Kejal D Gandhi http://orcid.org/0000-0003-3863-8977 Munish Sharma http://orcid.org/0000-0002-5881-5742 Pahnwat Tonya Taweesedt http://orcid.org/0000-0002-5791-6920 Salim Surani http://orcid.org/0000-0001-7105-4266
Funding Agency and Grant Number
Corresponding Author	Salim Surani, MD, Adjunct Professor, Department of Medicine, Texas A&M University, 701 Ayers Street, Corpus Christi, TX 78404, United States. srsurani@gmail.com
Key Words	COVID-19; Acute respiratory distress syndrome; Positive end-expiratory pressure; Proning; Ventilation management; Acute respiratory distress syndrome; Intensive care unit
Core Tip	Optimizing and titrating the positive end-expiratory pressure (PEEP) in acute respiratory distress syndrome (ARDS) patients has been studied widely in the critical care world. However, the ARDS caused by coronavirus disease 2019 (COVID-19) possesses a challenge due to relatively preserved compliance in the early phase of this disease and questions the guidelines which have been long established. Proning, though tedious and cumbersome, which has been traditionally proved to improve oxygenation and survival benefits in ARDS patients has been extensively applied in COVID-19 patients. This article critically analyzes the role of PEEP and proning in COVID-19 patients.
Publish Date	2021-09-09 09:23
Citation	Gandhi KD, Sharma M, Taweesedt PT, Surani S. Role of proning and positive end-expiratory pressure in COVID-19. World J Crit Care Med 2021; 10(5): 183-193
URL	https://www.wjgnet.com/2220-3141/full/v10/i5/183.htm
DOI	https://dx.doi.org/10.5492/wjccm.v10.i5.183

Full Article (PDF)	wjccm-10-183.pdf
Full Article (Word)	WJCCM-10-183.docx
Manuscript File	64665_Auto_Edited-JPY.docx
Answering Reviewers	64665-Answering reviewers.pdf
Audio Core Tip	64665-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64665-Conflict-of-interest statement.pdf
Copyright License Agreement	64665-Copyright license agreement.pdf
Peer-review Report	64665-Peer-review(s).pdf
Scientific Misconduct Check	64665-Bing-Wang JL-1.jpg
Scientific Misconduct Check	64665-Scientific misconduct check.pdf
Scientific Editor Work List	64665-Scientific editor work list.pdf
CrossCheck Report	64665-CrossCheck report.pdf