Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	64701
Country	China

Received	2021-02-22 13:20
Peer-Review Started	2021-02-22 13:25
To Make the First Decision
Return for Revision	2021-08-19 18:55
Revised	2021-09-08 16:50
Second Decision	2021-12-13 03:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-12-23 06:28
Articles in Press	2021-12-23 06:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-09 02:16
Typeset the Manuscript	2021-12-31 04:11
Publish the Manuscript Online	2022-01-11 00:11

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Biomarkers for response to immune checkpoint inhibitors in gastrointestinal cancers
Manuscript Source	Invited Manuscript
All Author List	Meng Li, Denis Kaili and Lei Shi
ORCID	Author(s) ORCID Number Meng Li http://orcid.org/0000-0002-2911-4293 Denis Kaili http://orcid.org/0000-0002-4843-9974 Lei Shi http://orcid.org/0000-0002-7995-5664
Funding Agency and Grant Number	Funding Agency Grant Number Fundamental Research Funds for the Central Universities 2019CDYGYB024
Corresponding Author	Lei Shi, PhD, Associate Professor, School of Life Sciences, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China. shil@cqu.edu.cn
Key Words	Immunotherapy; Immune Checkpoint Inhibitor; Biomarker; Predictive response; Gastrointestinal cancer
Core Tip	Cancer immunotherapy and immune checkpoint inhibitors (ICIs) have recently revolutionized gastrointestinal (GI) cancer treatment, providing unprecedented clinical benefits. However, GI patients treated with ICIs do not fully benefit, and therefore the identification and development of biomarkers for predicting ICIs response have become a pressing issue to be solved now. In this review, we summarize the use of predictive biomarkers for ICI-treatment in GI cancers, and discussed novel biomarkers under development. We also presented important biomarkers in other tumors with the aim of providing a cutting-edge reference for GI cancers research.
Publish Date	2022-01-11 00:11
Citation	Li M, Kaili D, Shi L. Biomarkers for response to immune checkpoint inhibitors in gastrointestinal cancers. World J Gastrointest Oncol 2022; 14(1): 19-37
URL	https://www.wjgnet.com/1948-5204/full/v14/i1/19.htm
DOI	https://dx.doi.org/10.4251/wjgo.v14.i1.19

Full Article (PDF)	WJGO-14-19.pdf
Full Article (Word)	WJGO-14-19.docx
Manuscript File	64701_Auto_Edited-JRF-Wang TQ.docx
Answering Reviewers	64701-Answering reviewers.pdf
Audio Core Tip	64701-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64701-Conflict-of-interest statement.pdf
Copyright License Agreement	64701-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	64701-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	64701-Language certificate.pdf
Peer-review Report	64701-Peer-review(s).pdf
Scientific Misconduct Check	64701-Bing-Fan JR-2.png
Scientific Editor Work List	64701-Scientific editor work list.pdf