Publication Name	World Journal of Gastroenterology
Manuscript ID	6471
Country	United States

Received	2013-10-19 11:09
Peer-Review Started	2013-10-22 13:40
To Make the First Decision	2014-01-24 14:26
Return for Revision	2014-01-26 14:16
Revised	2014-02-26 08:34
Second Decision	2014-04-29 12:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-29 14:20
Articles in Press	2014-05-23 10:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-17 09:38
Publish the Manuscript Online	2014-08-07 10:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Intestinal antigen-presenting cells in mucosal immune homeostasis: Crosstalk between dendritic cells, macrophages and B-cells
Manuscript Source	Invited Manuscript
All Author List	Elizabeth R Mann and Xuhang Li
Funding Agency and Grant Number
Corresponding Author	Xuhang Li, PhD, Assistant Professor of Medicine, Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Ave, Ross Research Bldg Rm 746, Baltimore, MD 21205, United States. xuhang@jhmi.edu
Key Words	Antigen presenting cells; Dendritic cells; Macrophages; B cells; Inflammatory bowel disease
Core Tip	The intestinal immune-system maintains a delicate balance between immunogenicity against invading pathogens and tolerance of the commensal microbiota. Inflammatory bowel disease involves a breakdown in tolerance towards the microbiota. Dendritic cells, macrophages and B-cells are known as professional antigen-presenting cells (APC) due to their specialization in presenting processed antigen to T-cells, and in turn shaping types of T-cell responses generated. Here, we present an updated knowledge toward the role of these APC in intestinal immunity, both in the steady state and in inflammation, and how they interact with one another and with the intestinal microenvironment to shape mucosal immune responses.
Publish Date	2014-08-07 10:34
Citation	Mann ER, Li X. Intestinal antigen-presenting cells in mucosal immune homeostasis: Crosstalk between dendritic cells, macrophages and B-cells. World J Gastroenterol 2014; 20(29): 9653-9664
URL	http://www.wjgnet.com/1007-9327/full/v20/i29/9653.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i29.9653

Full Article (PDF)	WJG-20-9653.pdf
Full Article (Word)	WJG-20-9653.doc
Manuscript File	6471-Review.docx
Answering Reviewers	6471-Answering reviewers.pdf
Copyright License Agreement	6471-Copyright assignment.pdf
Peer-review Report	6471-Peer reviews.pdf
Scientific Editor Work List	6471-Scientific editor work list.pdf