Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	64728
Country	Poland

Received	2021-02-22 19:39
Peer-Review Started	2021-02-22 19:41
To Make the First Decision
Return for Revision	2021-06-04 03:28
Revised	2021-06-17 20:21
Second Decision	2021-10-18 06:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-10-18 09:24
Articles in Press	2021-10-18 09:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-07 04:35
Publish the Manuscript Online	2021-12-14 23:58

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management
Manuscript Source	Invited Manuscript
All Author List	Beata Jabłońska, Paweł Szmigiel and Sławomir Mrowiec
ORCID	Author(s) ORCID Number Beata Jabłońska http://orcid.org/0000-0002-5495-2969 Paweł Szmigiel http://orcid.org/0000-0003-2973-1758 Sławomir Mrowiec http://orcid.org/0000-0003-2206-3144
Funding Agency and Grant Number
Corresponding Author	Beata Jabłońska, MD, PhD, Adjunct Professor, Department of Digestive Tract Surgery, Medical University of Silesia, Medyków 14, Katowice 40-752, Poland. bjablonska@poczta.onet.pl
Key Words	Pancreatic cyst; Pancreatic cystic neoplasm; Intraductal papillary mucinous neoplasm; Pancreatic cancer; Pancreatectomy; Guidelines
Core Tip	Intraductal papillary mucinous neoplasms (IPMNs) account about 1% of all pancreatic neoplasms and 25% of cystic neoplasms. We can distinguish three IPMN types: main duct-IPMN (MD-IPPMN), branch duct-IPMN (BD-IPMN), and mixed type-IPMN. Magnetic resonance imaging is the most useful approach for most IPMNs. Management depends on the type and radiological features of IPMNs. MD-IPMN is recommended for surgery. In BD-IPMN, management involves surgery or surveillance depending on the tumor size, cyst growth rate, solid components, main duct dilatation, high-grade dysplasia in cytology, the presence of symptoms (jaundice, new-onset diabetes, pancreatitis), and CA 19.9 serum level. The patient’s age and comorbidities should also be taken into consideration. Currently, there are different guidelines regarding the diagnostics and management of IPMNs: Sendai International Association of Pancreatology guidelines (2006), American Gastroenterological Association guidelines, revised international consensus Fukuoka guidelines (2012), revised international consensus Fukuoka guidelines (2017), and European evidence-based guidelines based on the European Study Group on Cystic Tumors of the Pancreas (2018). The experts of  Verona Evidence-Based Meeting 2020 determined the most important further directions regarding guidelines on IPMN management.
Publish Date	2021-12-14 23:58
Citation	Jabłońska B, Szmigiel P, Mrowiec S. Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management. World J Gastrointest Oncol 2021; 13(12): 1880-1895
URL	https://www.wjgnet.com/1948-5204/full/v13/i12/1880.htm
DOI	https://dx.doi.org/10.4251/wjgo.v13.i12.1880

Full Article (PDF)	WJGO-13-1880.pdf
Full Article (Word)	WJGO-13-1880.docx
Manuscript File	64728_Auto_Edited.docx
Answering Reviewers	64728-Answering reviewers.pdf
Audio Core Tip	64728-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64728-Conflict-of-interest_statement.pdf
Copyright License Agreement	64728-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	64728-Language certificate.pdf
Peer-review Report	64728-Peer-review(s).pdf
Scientific Misconduct Check	64728-Bing-Wu YXJ-2.jpg
Scientific Editor Work List	64728-Scientific editor work list.pdf
CrossCheck Report	64728-CrossCheck report.pdf