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Articles Published Processes
6/10/2022 2:05:28 AM | Browse: 245 | Download: 602
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Received |
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2021-02-23 02:51 |
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Peer-Review Started |
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2021-02-23 02:54 |
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To Make the First Decision |
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Return for Revision |
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2021-05-03 19:58 |
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Revised |
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2021-05-23 14:29 |
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Second Decision |
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2022-05-06 02:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-05-07 01:10 |
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Articles in Press |
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2022-05-07 01:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-03 00:34 |
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Typeset the Manuscript |
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2022-05-31 21:45 |
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Publish the Manuscript Online |
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2022-06-10 02:05 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Can dietary flavonoids be useful in the personalized treatment of colorectal cancer?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Cristina Pereira-Wilson |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Portuguese Foundation for Science and Technology (FCT) |
UIDB/04469/2020 |
| I&D&I AgriFood XXI |
NORTE-01-0145-FEDER-000041 |
| Fundo Europeu de Desenvolvimento Regional (FEDER) through the NORTE 2020 program (Programa Operacional Regional do Norte 2014/2020) |
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| Corresponding Author |
Cristina Pereira-Wilson, PhD, Assistant Professor, Department of Biology, Centre of Biological Engineering, LABBELS Associate Laboratory, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal. cpereira@bio.uminho.pt |
| Key Words |
Colorectal cancer; Personalized treatment; Quercetin; Curcumin; KRAS; BRAF |
| Core Tip |
Given the limited efficacy of therapeutic strategies for colorectal cancer presenting mutational activations in mitogen-activated protein kinase and/or PI3K pathways, developing combination therapies with natural flavonoids with demonstrated effects on these pathways may constitute a valuable path forward. Published results show quercetin and curcumin as possibly the best candidates to be further explored in the context of adjuvant colorectal cancer therapy either as part of dietary prescriptions or as purified compounds in combination treatment. Clinical trial data is still largely missing and is urgently needed to verify relevant effects and for the development of more personalized treatment approaches. |
| Publish Date |
2022-06-10 02:05 |
| Citation |
Pereira-Wilson C. Can dietary flavonoids be useful in the personalized treatment of colorectal cancer? World J Gastrointest Oncol 2022; 14(6): 1115-1123 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i6/1115.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i6.1115 |
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