Publication Name	World Journal of Stem Cells
Manuscript ID	64867
Country	France

Received	2021-02-24 15:42
Peer-Review Started	2021-02-24 15:44
To Make the First Decision
Return for Revision	2021-04-20 02:15
Revised	2021-04-28 17:36
Second Decision	2021-07-16 05:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-16 07:59
Articles in Press	2021-07-16 07:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-28 03:37
Typeset the Manuscript	2021-08-16 01:06
Publish the Manuscript Online	2021-08-20 05:46

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Review
Article Title	Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells
Manuscript Source	Invited Manuscript
All Author List	Mehdi Razazian, Maryam Khosravi, Sheyda Bahiraii, Georges Uzan, Sara Shamdani and Sina Naserian
ORCID	Author(s) ORCID Number Mehdi Razazian http://orcid.org/0000-0001-8806-6773 Maryam Khosravi http://orcid.org/0000-0002-9801-3023 Sheyda Bahiraii http://orcid.org/0000-0001-5112-8643 Georges Uzan http://orcid.org/0000-0002-0178-5386 Sara Shamdani http://orcid.org/0000-0002-3386-6500 Sina Naserian http://orcid.org/0000-0003-3604-8375
Funding Agency and Grant Number	Funding Agency Grant Number “l'Agence Nationale de la Recherche” in the form of ‘’programme d'Investissements d’avenir” ANR_15-RHUS60002 ‘’la Fondation de la Maison de la Chimie’’ for the project R20150LL RAK20150LLA
Corresponding Author	Sina Naserian, PhD, Director, Research Scientist, Institut national de la santé et de la recherche médicale (Inserm) Unité Mixte de Recherche-Inserm-Ministère de la Défense 1197, Hôpital Paul Brousse, Bâtiment Lavoisier, 12-14 avenue Paul Vaillant Couturier, Villejuif 94800, France. sina.naserian@inserm.fr
Key Words	Endothelial Progenitor Cells; Mesenchymal Stem Cells; T cells; Immunosuppression; Immunoregulation; TNFα-TNFR2 signaling pathway
Core Tip	This present article aims to review for the first time some known similarities and differences between mesenchymal stem cells and endothelial progenitor cells’ immunomodulatory functions. It describes and compares different mechanisms that they use to suppress conventional T cells and/or to induce regulatory T cells. Among different mechanisms of action, we emphasize the implication of the immune checkpoint signaling pathways such as the tumor necrosis factor alpha-tumor necrosis factor receptor 2 axis. We try to cover the lack of information by proposing new research paths and their importance for future studies including in-vitro and in-vivo applications in regenerative medicine.
Publish Date	2021-08-20 05:46
Citation	Razazian M, Khosravi M, Bahiraii S, Uzan G, Shamdani S, Naserian S. Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells. World J Stem Cells 2021; 13(8): 971-984
URL	https://www.wjgnet.com/1948-0210/full/v13/i8/971.htm
DOI	https://dx.doi.org/10.4252/wjsc.v13.i8.971

Full Article (PDF)	WJSC-13-971.pdf
Full Article (Word)	WJSC-13-971.docx
Manuscript File	64867-Review-Filipodia-CL.docx
Answering Reviewers	64867-Answering reviewers.pdf
Audio Core Tip	64867-Audio core tip.ogg
Conflict-of-Interest Disclosure Form	64867-Conflict-of-interest statement.pdf
Copyright License Agreement	64867-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	64867-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	64867-Language certificate.pdf
Peer-review Report	64867-Peer-review(s).pdf
Scientific Misconduct Check	64867-Bing-Wang JL-1.jpg
Scientific Misconduct Check	64867-Bing-Liu M-2.png
Scientific Misconduct Check	64867-Scientific misconduct check.pdf
Scientific Editor Work List	64867-Scientific editor work list.pdf