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Articles Published Processes
6/26/2021 7:48:01 AM | Browse: 610 | Download: 1094
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Received |
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2021-02-25 19:17 |
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Peer-Review Started |
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2021-02-25 19:22 |
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To Make the First Decision |
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Return for Revision |
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2021-04-20 01:56 |
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Revised |
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2021-05-02 09:20 |
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Second Decision |
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2021-06-04 08:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-06-04 09:18 |
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Articles in Press |
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2021-06-04 09:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-11 20:48 |
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Typeset the Manuscript |
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2021-06-23 03:30 |
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Publish the Manuscript Online |
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2021-06-26 07:48 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Harpreet K Mandhair, Urban Novak and Ramin Radpour |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ramin Radpour, MSc, PhD, Lecturer, Senior Scientist, Department for BioMedical Research, University of Bern, Murtenstrasse 35, Bern 3008, Switzerland. ramin.radpour@dbmr.unibe.ch |
| Key Words |
Autophagy; Cancer stem cells; Cancer cells; Epigenetics; Histone remodeling; DNA methylation; Non-coding RNA |
| Core Tip |
Cancer stem cells (CSCs) are a distinct population in the tumor bulk with enhanced self-renewal capability. Autophagy primarily exerts oncogenic activity and adaptive signals during cancer progression. Similarly, epigenetic modifications display a crucial role in tumor initiation and cancer development through its regulation of tumor suppressor genes and oncogenes. Emerging studies report epigenetic modifications regulate autophagy and metabolic pathways promoting tumor growth, elicit immunosuppressive activity and contribute to therapy resistance. Therefore, understanding this complex signaling patterns can theoretically lead to a more efficient and targeted cancer treatment. |
| Publish Date |
2021-06-26 07:48 |
| Citation |
Mandhair HK, Novak U, Radpour R. Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells. World J Stem Cells 2021; 13(6): 542-567 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i6/542.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i6.542 |
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