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Articles Published Processes
9/18/2021 9:35:02 AM | Browse: 418 | Download: 602
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Received |
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2021-03-01 07:32 |
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Peer-Review Started |
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2021-03-01 07:38 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 18:21 |
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Revised |
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2021-05-03 07:57 |
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Second Decision |
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2021-08-09 02:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-09 05:29 |
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Articles in Press |
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2021-08-09 05:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-26 03:33 |
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Typeset the Manuscript |
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2021-09-16 01:54 |
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Publish the Manuscript Online |
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2021-09-18 09:35 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Review |
| Article Title |
Stem cells' centrosomes: How can the organelles identified 130 years ago contribute to the future of regenerative medicine?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Andreas Goutas and Varvara Trachana |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Varvara Trachana, PhD, Assistant Professor, Department of Biology, Faculty of Medicine, University of Thessaly, 3, Panepistimiou str, Larisa 41500, Biopolis, Greece. vtrachana@med.uth.gr |
| Key Words |
Centrosome; Primary cilium; Asymmetry; Self-renewal; Differentiation; Stemness |
| Core Tip |
It is believed that the major difficulties that regenerative medicine currently faces are exactly those expected to be resolved by stem cell‐based therapies. These therapies demand a comprehensive understanding of stem cells’ asymmetric division, in order to be able to manipulate stem cells’ fate. Here, we are reporting studies that prove that the centrosome — and centrosome-derived primary cilium — is providing an excellent vehicle that serves the asymmetric distribution of cell fate determinants. We are anticipating that sufficient evidence is being provided, that will place this organelle at the center of the efforts that will shape the future of regenerative medicine. |
| Publish Date |
2021-09-18 09:35 |
| Citation |
Goutas A, Trachana V. Stem cells' centrosomes: How can the organelles identified 130 years ago contribute to the future of regenerative medicine? World J Stem Cells 2021; 13(9): 1177-1196 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i9/1177.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i9.1177 |
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