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Articles Published Processes
8/5/2021 2:37:04 PM | Browse: 364 | Download: 812
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Received |
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2021-03-04 10:16 |
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Peer-Review Started |
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2021-03-04 10:16 |
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To Make the First Decision |
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Return for Revision |
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2021-04-04 16:58 |
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Revised |
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2021-04-08 16:46 |
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Second Decision |
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2021-05-14 09:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-15 04:51 |
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Articles in Press |
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2021-05-15 04:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-23 10:30 |
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Typeset the Manuscript |
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2021-08-02 07:55 |
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Publish the Manuscript Online |
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2021-08-05 14:37 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Expression of Caspase-3 and hypoxia inducible factor 1α in hepatocellular carcinoma patients complicated by hemorrhage and necrosis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hui Liang, Jian-Guo Wu, Fei Wang, Bo-Xuan Chen, Shi-Tian Zou, Cong Wang and Shuai-Wu Luo |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Research Project for Jiangxi Educational Department |
180086 |
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Corresponding Author |
Jian-Guo Wu, PhD, Chief Doctor, Department of Nuclear Medicine, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Donghu District, Nanchang 330006, Jiangxi Province, China. grantwu2021@163.com |
Key Words |
Hepatocellular carcinoma; Caspase-3; Hypoxia inducible factor 1α; Hemorrhage; Necrosis; Prognosis |
Core Tip |
It was confirmed that the expression of Caspase-3 in hepatocellular carcinoma (HCC) complicated with hemorrhagic and necrotic pathological changes decreased and the expression of hypoxia inducible factor 1α (HIF-1α) mRNA increased, which was related to the clinicopathological features and prognosis. This study explored the expression characteristics of the Caspase-3 and the HIF-1α in tissues, and their relationship with the biological behavior with HCC complicated by the hemorrhage and necrosis. It also provided help for the further clinical biological behavior so as to judge the prognosis. |
Publish Date |
2021-08-05 14:37 |
Citation |
Liang H, Wu JG, Wang F, Chen BX, Zou ST, Wang C, Luo SW. Expression of Caspase-3 and hypoxia inducible factor 1α in hepatocellular carcinoma patients complicated by hemorrhage and necrosis. World J Clin Cases 2021; 9(23): 6725-6733 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i23/6725.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i23.6725 |
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