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8/5/2021 2:37:04 PM | Browse: 254 | Download: 443
Publication Name World Journal of Clinical Cases
Manuscript ID 65066
Country China
Received
2021-03-04 10:16
Peer-Review Started
2021-03-04 10:16
To Make the First Decision
Return for Revision
2021-04-04 16:58
Revised
2021-04-08 16:46
Second Decision
2021-05-14 09:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-15 04:51
Articles in Press
2021-05-15 04:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-23 10:30
Typeset the Manuscript
2021-08-02 07:55
Publish the Manuscript Online
2021-08-05 14:37
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Expression of Caspase-3 and hypoxia inducible factor 1α in hepatocellular carcinoma patients complicated by hemorrhage and necrosis
Manuscript Source Unsolicited Manuscript
All Author List Hui Liang, Jian-Guo Wu, Fei Wang, Bo-Xuan Chen, Shi-Tian Zou, Cong Wang and Shuai-Wu Luo
ORCID
Author(s) ORCID Number
Hui Liang http://orcid.org/0000-0002-2929-700x
Jian-Guo Wu http://orcid.org/0000-0003-1204-1697
Fei Wang http://orcid.org/0000-0003-0010-7652
Bo-Xuan Chen http://orcid.org/0000-0002-5086-4988
Shi-Tian Zou http://orcid.org/0000-0002-7878-8470
Cong Wang http://orcid.org/0000-0003-1561-8914
Shuai-Wu Luo http://orcid.org/0000-0003-0904-7430
Funding Agency and Grant Number
Funding Agency Grant Number
Research Project for Jiangxi Educational Department 180086
Corresponding Author Jian-Guo Wu, PhD, Chief Doctor, Department of Nuclear Medicine, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Donghu District, Nanchang 330006, Jiangxi Province, China. grantwu2021@163.com
Key Words Hepatocellular carcinoma; Caspase-3; Hypoxia inducible factor 1α; Hemorrhage; Necrosis; Prognosis
Core Tip It was confirmed that the expression of Caspase-3 in hepatocellular carcinoma (HCC) complicated with hemorrhagic and necrotic pathological changes decreased and the expression of hypoxia inducible factor 1α (HIF-1α) mRNA increased, which was related to the clinicopathological features and prognosis. This study explored the expression characteristics of the Caspase-3 and the HIF-1α in tissues, and their relationship with the biological behavior with HCC complicated by the hemorrhage and necrosis. It also provided help for the further clinical biological behavior so as to judge the prognosis.
Publish Date 2021-08-05 14:37
Citation Liang H, Wu JG, Wang F, Chen BX, Zou ST, Wang C, Luo SW. Expression of Caspase-3 and hypoxia inducible factor 1α in hepatocellular carcinoma patients complicated by hemorrhage and necrosis. World J Clin Cases 2021; 9(23): 6725-6733
URL https://www.wjgnet.com/2307-8960/full/v9/i23/6725.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i23.6725
Full Article (PDF) WJCC-9-6725.pdf
Full Article (Word) WJCC-9-6725.docx
Manuscript File 65066_Auto_Edited_WangTQ.docx
Answering Reviewers 65066-Answering reviewers.pdf
Audio Core Tip 65066-Audio core tip.m4a
Biostatistics Review Certificate 65066-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 65066-Conflict-of-interest statement.pdf
Copyright License Agreement 65066-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65066-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 65066-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 65066-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 65066-Language certificate.pdf
Peer-review Report 65066-Peer-review(s).pdf
Scientific Misconduct Check 65066-Scientific misconduct check.pdf
Scientific Editor Work List 65066-Scientific editor work list.pdf