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Articles Published Processes
11/24/2021 9:54:22 AM | Browse: 384 | Download: 657
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Received |
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2021-02-27 17:51 |
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Peer-Review Started |
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2021-02-27 17:53 |
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To Make the First Decision |
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Return for Revision |
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2021-05-02 23:58 |
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Revised |
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2021-05-07 20:51 |
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Second Decision |
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2021-08-20 02:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-20 06:20 |
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Articles in Press |
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2021-08-20 06:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-10-03 21:53 |
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Typeset the Manuscript |
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2021-11-19 02:19 |
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Publish the Manuscript Online |
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2021-11-24 09:54 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Chelation therapy in liver diseases of childhood: Current status and response
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jayendra Seetharaman and Moinak Sen Sarma |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Moinak Sen Sarma, MBBS, MD, Assistant Professor, Department of Pediatric Gastroenterology, Sanjay Gandhi Post-graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. moinaksen@gmail.com |
| Key Words |
Wilson’s disease; D-Penicillamine; Trientine; Indian childhood cirrhosis; Deferoxamine; Deferasirox; Hemochromatosis |
| Core Tip |
Chelation forms the most important part of management of certain liver diseases in children. In Wilson's disease and secondary hemochromatosis related to transfusion, chelation is well established treatment modality with proven efficacy. In other diseases like copper associated childhood cirrhosis and neonatal hemochromatosis the role of chelation is doubtful. In Herediatary hemochromatosis, chelation is recommended as alternative therapy. The selection of chelating agents for treatment depends on the efficacy, feasibility and risk of adverse effects known from literature. The review discusses the concepts of chelation and reviews the literature to assess the role of chelation in treatment of various pediatric liver diseases. |
| Publish Date |
2021-11-24 09:54 |
| Citation |
Seetharaman J, Sarma MS. Chelation therapy in liver diseases of childhood: Current status and response. World J Hepatol 2021; 13(11): 1552-1567 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i11/1552.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i11.1552 |
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