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Articles Published Processes
9/17/2021 8:43:53 AM | Browse: 499 | Download: 1039
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Received |
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2021-02-28 09:50 |
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Peer-Review Started |
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2021-02-28 09:59 |
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To Make the First Decision |
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Return for Revision |
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2021-04-27 04:54 |
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Revised |
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2021-05-09 12:57 |
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Second Decision |
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2021-08-12 03:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-12 07:04 |
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Articles in Press |
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2021-08-12 07:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-31 02:39 |
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Typeset the Manuscript |
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2021-09-10 05:49 |
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Publish the Manuscript Online |
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2021-09-17 08:43 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Real world evidence on first and second line palliative chemotherapy in advanced pancreatic cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hakon Blomstrand, Atul Batra, Winson Y Cheung and Nils Oskar Elander |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nils Oskar Elander, MD, PhD, Doctor, Doctor, Department of Biomedical and Clinical Sciences, Linköping University, Linköping University Hospital, Linköping 58185, Sweden. nils.elander@liu.se |
| Key Words |
Pancreatic cancer; Palliative therapy; Cancer chemotherapy; Gemcitabine; Paclitaxel, nano albumin-bound; Folfirinox |
| Core Tip |
This paper summarizes and interprets published real world evidence (RWE) on treatment strategies in advanced pancreatic cancer. The real world outcomes of first line chemotherapy regimens such as Folfirinox and gemcitabine/nab-paclitaxel are thoroughly reviewed. The results of randomized controlled trials (RCTs) exploring these regimens seem to be largely generalizable in a real world context. On second line options, i.e. salvage chemotherapy following failure of the first line therapy, significant uncertainties remain. Additional RCTs and RWE studies addressing current and novel regimens, and the optimal sequence of these, are highly needed. |
| Publish Date |
2021-09-17 08:43 |
| Citation |
Blomstrand H, Batra A, Cheung WY, Elander NO. Real world evidence on first- and second-line palliative chemotherapy in advanced pancreatic cancer. World J Clin Oncol 2021; 12(9): 787-799 |
| URL |
https://www.wjgnet.com/2218-4333/full/v12/i9/787.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v12.i9.787 |
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